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  3. RMC-5552

RMC-5552 

Cat. No.: HY-132168
Handling Instructions

RMC-5552 is a potent and selective inhibitor of mTORC1. RMC-5552 inhibits phosphorylation of mTORC1 pS6K and p4EBP1 with IC50s of 0.14 nM and 0.48 nM, respectively. RMC-5552 has anti-cancer activity.

For research use only. We do not sell to patients.

RMC-5552 Chemical Structure

RMC-5552 Chemical Structure

CAS No. : 2382768-62-7

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Description

RMC-5552 is a potent and selective inhibitor of mTORC1. RMC-5552 inhibits phosphorylation of mTORC1 pS6K and p4EBP1 with IC50s of 0.14 nM and 0.48 nM, respectively. RMC-5552 has anti-cancer activity.

IC50 & Target

mTORC1

 

Clinical Trial
Molecular Weight

1778.13

Formula

C₉₃H₁₃₆N₁₀O₂₄

CAS No.
SMILES

NC1=C(C2=NC=N1)C(C3=CC=C(O4)C(N=C4N)=C3)=NN2CC5=CC=C(C6)C(CCN6C(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(O[[email protected]](CC[[email protected]]7C[[email protected]]([[email protected]@](C[[email protected]]([[email protected]@H](/C=C([[email protected]]([[email protected]](C([[email protected]@H](C[[email protected]@H]8C)C)=O)OC)O)\C)C)O)([H])OC([[email protected]@](CCCC9)([H])N9C(C([[email protected]](O[[email protected]]%10([H])C[[email protected]@H](/C(C)=C/C=C/C=C/8)OC)([[email protected]@H](CC%10)C)O)=O)=O)=O)C)[[email protected]@H](C7)OC)=O)=O)=C5

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Keywords:

RMC-5552RMC5552RMC 5552mTORMammalian target of Rapamycinsignalingpathway4EBP1S6Kphosphorylationanti-cancersolidtumorsInhibitorinhibitorinhibit

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RMC-5552
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