2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. S-Adenosyl-L-methionine-d3

S-Adenosyl-L-methionine-d3  (Synonyms: S-Adenosyl methionine-d3; Ademetionine-d3; AdoMet-d3)

Cat. No.: HY-B0617S Purity: ≥95.0%
COA Handling Instructions

Molarity Calculator

S-Adenosyl-L-methionine-d3 is the deuterated product of S-Adenosyl-L-methionine. S-Adenosyl-L-methionine is endogenously produced from methionine and ATP through the action of methionine adenosyltransferase and is an important orally active methyl donor.

For research use only. We do not sell to patients.

S-Adenosyl-L-methionine-d<sub>3</sub> Chemical Structure

S-Adenosyl-L-methionine-d3 Chemical Structure

CAS No. : 68684-40-2

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1 mg USD 680 In-stock
5 mg USD 1500 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of S-Adenosyl-L-methionine-d3:

S-Adenosyl-L-methionine-d3 Related Antibodies

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Description

S-Adenosyl-L-methionine-d3 is the deuterated product of S-Adenosyl-L-methionine. S-Adenosyl-L-methionine is endogenously produced from methionine and ATP through the action of methionine adenosyltransferase and is an important orally active methyl donor[1][2].

Molecular Weight

401.46

Formula

C15H19D3N6O5S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@](O[C@@H]([C@H]1O)C[S+](C([2H])([2H])[2H])CC[C@H](N)C([O-])=O)([H])N2C3=NC=NC(N)=C3N=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (124.55 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4909 mL 12.4545 mL 24.9091 mL
5 mM 0.4982 mL 2.4909 mL 4.9818 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 98.05%

COA (253 KB) HNMR (178 KB) LCMS (131 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.4909 mL 12.4545 mL 24.9091 mL 62.2727 mL
5 mM 0.4982 mL 2.4909 mL 4.9818 mL 12.4545 mL
10 mM 0.2491 mL 1.2455 mL 2.4909 mL 6.2273 mL
15 mM 0.1661 mL 0.8303 mL 1.6606 mL 4.1515 mL
20 mM 0.1245 mL 0.6227 mL 1.2455 mL 3.1136 mL
25 mM 0.0996 mL 0.4982 mL 0.9964 mL 2.4909 mL
30 mM 0.0830 mL 0.4152 mL 0.8303 mL 2.0758 mL
40 mM 0.0623 mL 0.3114 mL 0.6227 mL 1.5568 mL
50 mM 0.0498 mL 0.2491 mL 0.4982 mL 1.2455 mL
60 mM 0.0415 mL 0.2076 mL 0.4152 mL 1.0379 mL
80 mM 0.0311 mL 0.1557 mL 0.3114 mL 0.7784 mL
100 mM 0.0249 mL 0.1245 mL 0.2491 mL 0.6227 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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S-Adenosyl-L-methionine-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

S-Adenosyl-L-methionine-d368684-40-2S-Adenosyl methionine-d3Ademetionine-d3AdoMet-d3Endogenous MetaboliteDeuteriummethionineATPadenosyltransferasemethylgroupdonorInhibitorinhibitorinhibit

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