1. Others

Ademetionine (Synonyms: S-Adenosyl-L-methionine; S-Adenosyl methionine; SAMe; AdoMet)

Cat. No.: HY-B0617 Purity: >98.0%
Handling Instructions

Ademetionine(S-adenosyl-l-methionine; SAMe) is a naturally-occurring substance which is a major source of methyl groups in the brain.

For research use only. We do not sell to patients.

Ademetionine Chemical Structure

Ademetionine Chemical Structure

CAS No. : 29908-03-0

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in Water USD 77 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
50 mg USD 70 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
100 mg USD 90 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
500 mg USD 280 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Other Forms of Ademetionine:

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Ademetionine(S-adenosyl-l-methionine; SAMe) is a naturally-occurring substance which is a major source of methyl groups in the brain. Target: Others S-adenosyl-l-methionine (SAMe) is a naturally-occurring substance which is a major source of methyl groups in the brain. The efficacy of SAMe in treating depressive syndromes and disorders is superior with that of placebo and comparable to that of standard tricyclic antidepressants. Since SAMe is a naturally occurring compound with relatively few side-effects, it is a potentially important treatment for depression [1]. S-adenosylmethionine (SAMe) is a dietary supplement used in the management of osteoarthritis (OA) symptoms. Studies evaluating SAMe in the management of OA have been limited to Non Steroidal Anti-inflammatory Drugs (NSAIDs) for comparison. The present study compares the effectiveness of SAMe to a cyclooxygenase-2 (COX-2) inhibitor (celecoxib) for pain control, functional improvement and to decrease side effects in people with osteoarthritis of the knee [2].

Clinical Trial
References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 2.5098 mL 12.5489 mL 25.0979 mL
5 mM 0.5020 mL 2.5098 mL 5.0196 mL
10 mM 0.2510 mL 1.2549 mL 2.5098 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

398.44

Formula

C₁₅H₂₂N₆O₅S

CAS No.

29908-03-0

SMILES

O[[email protected]@H]([[email protected]]([[email protected]](N1C=NC2=C1N=CN=C2N)O3)O)[[email protected]]3C[S+](CC[[email protected]](N)C([O-])=O)C

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

H2O: ≥ 43 mg/mL; DMSO: ≥100 mg/mL (Need ultrasonic)

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

Purity: >98.0%

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Product Name:
Ademetionine
Cat. No.:
HY-B0617
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