1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite

5'-Methylthioadenosine (Synonyms: 5'-(Methylthio)-5'-deoxyadenosine; 5'-Deoxy-5'-(methylthio)adenosine; 5'-S-Methyl-5'-thioadenosine)

Cat. No.: HY-16938 Purity: >97.0%
Handling Instructions

5'-Methylthioadenosine is produced from S-adenosylmethionine and behaves as a powful inhibitory product.

For research use only. We do not sell to patients.

5'-Methylthioadenosine Chemical Structure

5'-Methylthioadenosine Chemical Structure

CAS No. : 2457-80-9

Size Price Stock Quantity
10 mM * 1 mL USD 55 In-stock
Estimated Time of Arrival: December 31
25 mg USD 50 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

5'-Methylthioadenosine is produced from S-adenosylmethionine and behaves as a powful inhibitory product.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

5'-Methylthioadenosine (MTA) can affect cellular processes in many ways. 5'-Methylthioadenosine has been shown to influence numerous critical responses of the cell including regulation of gene expression, proliferation, differentiation and apoptosis. Although most of these responses have been observed at the pharmacological level, their specificity makes it tempting to speculate that endogenous 5'-Methylthioadenosine could play a regulatory role in the cell. Finally, observations carried out in models of liver damage and cancer demonstrate a therapeutic potential for 5'-Methylthioadenosine that deserves further consideration[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3633 mL 16.8163 mL 33.6327 mL
5 mM 0.6727 mL 3.3633 mL 6.7265 mL
10 mM 0.3363 mL 1.6816 mL 3.3633 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

297.33

Formula

C₁₁H₁₅N₅O₃S

CAS No.

2457-80-9

SMILES

O[[email protected]@H]([[email protected]]([[email protected]](N1C=NC2=C1N=CN=C2N)O3)O)[[email protected]]3CSC

Storage

-20°C, protect from light

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
5'-Methylthioadenosine
Cat. No.:
HY-16938
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5'-Methylthioadenosine

Cat. No.: HY-16938