5'-Methylthioadenosine (Standard)
Based on 1 Customer Validation
5'-Methylthioadenosine (Standard) is the analytical standard of 5'-Methylthioadenosine. This product is intended for research and analytical applications. 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis[1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2].
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 97.01%
- CAS 番号: 2457-80-9
- 分子式: C11H15N5O3S
- 分子量:297.34
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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化学情報
- 純度とドキュメンテーション
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Help & FAQs
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HY-16938
5'-MethylthioadenosineSAM Metabolite -
HY-B0228
AdenosineEndogenous Autacoid -
HY-B0228R
Adenosine (Standard)Endogenous Autacoid -
HY-B0158
CytidineNucleoside Molecule -
HY-B0158R
Cytidine (Standard)Nucleoside Molecule -
HY-B0152
AdenineNucleobase -
HY-17413
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HY-B0083
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HY-N0157
Orotic acidActive Compound -
HY-17423
AbacavirReverse Transcriptase Inhibitor -
HY-A0168
RegadenosonVasodilator/A2A Adenosine Receptor Agonist -
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PenciclovirAnti-herpesvirus Agent
Product Information
説明
アプリケーション
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
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CAS 番号 2457-80-9
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性状 Solid
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分子量 297.34
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分子式 C11H15N5O3S
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Color White to off-white
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SMILES
NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CSC)O3
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別名
5'-(Methylthio)-5'-deoxyadenosine (Standard); 5'-Deoxy-5'-(methylthio)adenosine (Standard); 5'-S-Methyl-5'-thioadenosine (Standard)
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Yaofeng Li, et al. 5'-Methylthioadenosine and Cancer: old molecules, new understanding. J Cancer. 2019;10(4):927-936. [Content Brief]
[2]. Tang Y, et al. 5'-Methylthioadenosine attenuates ischemia reperfusion injury after liver transplantation in rats. Inflammation. 2014;37(5):1366-1373. [Content Brief]
[4]. Tang B, et al. Specific Targeting of MTAP-Deleted Tumors with a Combination of 2'-Fluoroadenine and 5'-Methylthioadenosine. Cancer Res. 2018;78(15):4386-4395. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
5'-Methylthioadenosine (Standard) 関連分類
HY-16938R 関連分類
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Keywords
- 5'-Methylthioadenosine (Standard)
- 2457-80-9
- 5'-(Methylthio)-5'-deoxyadenosine (Standard)
- 5'-Deoxy-5'-(methylthio)adenosine (Standard)
- 5'-S-Methyl-5'-thioadenosine (Standard)
- Reference Standards
- Endogenous Metabolite
- Apoptosis
- Parasite
- MTA
- SAM
- cancer
- 5'-Methylthioadenosine
- fluoroadenine
- NIH3T3
- nucleoside
- MTAP?
- MTAP+
- Inhibitor
- inhibitor
- inhibit