2. Others Metabolic Enzyme/Protease Apoptosis
  3. Isotope-Labeled Compounds Endogenous Metabolite Apoptosis
  4. S-Adenosyl-L-methionine-13C

S-Adenosyl-L-methionine-13C  (Synonyms: S-Adenosyl methionine-13C; Ademetionine-13C; AdoMet-13C)

Cat. No.: HY-B0617S1 Purity: 99.93%
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Handling Instructions Technical Support

S-Adenosyl-L-methionine-13C (S-Adenosyl methionine-13C) is the 13C labeled S-Adenosyl-L-methionine (HY-B0617). S-Adenosyl-L-methionine (S-Adenosyl methionine) is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects, and has the potential for liver disease and osteoarthritis research.

For research use only. We do not sell to patients.

S-Adenosyl-L-methionine-<sup>13</sup>C

S-Adenosyl-L-methionine-13C Chemical Structure

CAS No. : 74084-24-5

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Based on 1 publication(s) in Google Scholar

Other Forms of S-Adenosyl-L-methionine-13C:

S-Adenosyl-L-methionine-13C Related Antibodies

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Description

S-Adenosyl-L-methionine-13C (S-Adenosyl methionine-13C) is the 13C labeled S-Adenosyl-L-methionine (HY-B0617). S-Adenosyl-L-methionine (S-Adenosyl methionine) is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects, and has the potential for liver disease and osteoarthritis research[1][2][3].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

S-Adenosyl-L-methionine-13C Related Antibodies
Molecular Weight

399.43

Formula

C1413CH22N6O5S
CAS No.
Unlabeled CAS
Appearance

Solid

Color

White to yellow

SMILES

NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](C[S+]([13CH3])CC[C@H](N)C([O-])=O)O3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (125.18 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5036 mL 12.5178 mL 25.0357 mL
5 mM 0.5007 mL 2.5036 mL 5.0071 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.5036 mL 12.5178 mL 25.0357 mL 62.5892 mL
5 mM 0.5007 mL 2.5036 mL 5.0071 mL 12.5178 mL
10 mM 0.2504 mL 1.2518 mL 2.5036 mL 6.2589 mL
15 mM 0.1669 mL 0.8345 mL 1.6690 mL 4.1726 mL
20 mM 0.1252 mL 0.6259 mL 1.2518 mL 3.1295 mL
25 mM 0.1001 mL 0.5007 mL 1.0014 mL 2.5036 mL
30 mM 0.0835 mL 0.4173 mL 0.8345 mL 2.0863 mL
40 mM 0.0626 mL 0.3129 mL 0.6259 mL 1.5647 mL
50 mM 0.0501 mL 0.2504 mL 0.5007 mL 1.2518 mL
60 mM 0.0417 mL 0.2086 mL 0.4173 mL 1.0432 mL
80 mM 0.0313 mL 0.1565 mL 0.3129 mL 0.7824 mL
100 mM 0.0250 mL 0.1252 mL 0.2504 mL 0.6259 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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S-Adenosyl-L-methionine-13C Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

S-Adenosyl-L-methionine-13C74084-24-5S-Adenosyl methionine-13C Ademetionine-13C AdoMet-13CIsotope-Labeled CompoundsEndogenous MetaboliteApoptosisInhibitorinhibitorinhibit

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