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L-Methionine

10 Cited Publications
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Based on 10 publication(s) in Google Scholar

L-Methionine is an L-isomer of orally active Methionine, an essential amino acid. Methionine is a strong liver antidote that acts as a liver protector. L-Methionine can inhibit cell proliferation and induce cell apoptosis. L-Methionine has antitumor and antioxidant activity.

For research use only. We do not sell to patients.

  • Purity: 99.84%
  • CAS No.: 63-68-3
  • Formula: C5H11NO2S
  • Molecular Weight:149.22
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • L-Methionine Chemical Structure
    L-Methionine Chemical Structure
  • Experimental Validation Results for L-Methionine
  • Experimental Validation Results for L-Methionine
  • Experimental Validation Results for L-Methionine
  • Experimental Validation Results for L-Methionine
  • Experimental Validation Results for L-Methionine
CAS No.: 63-68-3
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WBELISAIHCIn Vivo Efficacy StudyFlow Cytometry
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  • L-Methionine Chemical Structure
    L-Methionine Chemical Structure
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    L-Methionine purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Mar 24:e2501623. [Abstract]

    Customer Validation
     The expression and secretion of PCSK9 in human with methionine deprivation for 6 h and then methionine (0-50 μM) supplementation for 24h. Immunoblotting analysis of PCSK9 in human CRC cell lines (SW480, SW620, HCT116, and LoVo).

  • 1/16

    L-Methionine purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Mar 24:e2501623. [Abstract]

    Customer Validation
     L-Methionine (0, 20, 50 μM). ELISA analysis of PCSK9 in culture supernatant of human CRC cell lines (SW480, SW620, HCT116, and LoVo).

  • 1/16

    L-Methionine purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Mar 24:e2501623. [Abstract]

    Customer Validation
     Mice were housed on either a normal diet (ND) with 0.86% methionine or a dietary methionine restriction (DMR) diet with 0.12% methionine from the day after injection until the endpoints. Immunohistochemistry analysis of PCSK9 in tumors from MC38‐ (n = 9) and Colon 26‐ (n = 4 (ND), n = 8 (DMR)) bearing mice fed with normal diet and methionine restriction diet (left). The abundance of PCSK9 was assessed (right).

  • 1/16

    L-Methionine purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Mar 24:e2501623. [Abstract]

    Customer Validation
     Mice were housed on either a normal diet (ND) with 0.86% methionine or a dietary methionine restriction (DMR) diet with 0.12% methionine from the day after injection until the endpoints. Tumor volume of PCSK9‐KD (n = 10) or PCSK9‐KO (n = 9) MC38‐bearing mice fed with normal diet and methionine restriction diet. EAA, essential amino acid; NEEA, non‐essential amino acid; CM, complete medium; ND, normal diet; DMR, dietary methionine restriction.

  • 1/16

    L-Methionine purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Mar 24:e2501623. [Abstract]

    Customer Validation
     Mice were housed on either a normal diet (ND) with 0.86% methionine or a dietary methionine restriction (DMR) diet with 0.12% methionine from the day after injection until the endpoints. Flow cytometric analysis of TNFα and Granzyme B in intratumoral CD8+T cells from Colon 26‐bearing mice fed with a methionine restriction diet alone or in combination with anti‐PD‐1 therapy.

  • L-Methionine