Cat. No.: HY-N0325

DL-Methionine

2 Cited Publications

Customer Review

Based on 2 publication(s) in Google Scholar

DL-Methionine is an essential amino acid containing sulfur with oxidative stress defense effects. DL-Methionine can be used for animal natural feed. DL-Methionine also kills H. rostochiensis on potato plants.

For research use only. We do not sell to patients.

Purity: 98.0%
CAS No.: 59-51-8
Formula: C₅H₁₁NO₂S
Molecular Weight:149.22

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

DL-Methionine Chemical Structure

CAS No.: 59-51-8

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
Publications (2)
Solvent & Solubility
- In Vitro
- In Vivo
Purity & Documentation
References
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

H. rostochiensis^[1]

All Parasite Isoforms :

In Vitro

The impact of DL-Methionine supplementation on animal performance interacts strongly with the crude protein (CP) content of the diet. Supplementation of DLM to a 20% crude protein diet for broilers reduces their abdominal fat weight, whereas this is not the case when the diet contained 23% CP. Breast meat yield is increased and abdominal fat content is decreased with increasing DL-Methionine supplementation, and this response is more pronounced in chickens reared on a diet with a lower protein level (20.5% CP) compared with a higher protein level (26%)^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

DL-methionine significantly decreases the numbers of males, females, cysts and eggs of H. rostochiensis on potato plants. DL-methionine kills almost all the nematodes when applied 3 days after inoculation, and DL-methionine does not affect plant growth adversely^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 59-51-8
Appearance Solid
Molecular Weight 149.22
Formula C₅H₁₁NO₂S
Color White to off-white
SMILES

NC(CCSC)C(O)=O
Structure Classification
- Amino acids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Publications (2)

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Aquac Rep

2025 Apr 15.
Vet Microbiol

The Chinese medicine monomer Schisandrin C inhibits PRRSV infection by regulating the OGT-PI3K/AKT/mTOR signaling pathway. [Abstract]

2026 May:316:110992. PMID: 41865607

Solvent & Solubility

In Vitro:

1M HCl : 100 mg/mL (670.15 mM; ultrasonic and adjust pH to 1 with HCl)

H₂O : 33.33 mg/mL (223.36 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

6.7015 mL

33.5076 mL

67.0151 mL

5 mM

1.3403 mL

6.7015 mL

13.4030 mL

10 mM

0.6702 mL

3.3508 mL

6.7015 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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In Vivo:

Working Solution

For the following dissolution methods, please prepare the working solution directly:

It is recommended to prepare fresh solutions and use them promptly within a short period of time.

The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS

Solubility: 10 mg/mL (67.02 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (283 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. K. evans, et al. Effects of amino acids on the reproduction of Heterodera rostochiensis. Nematologica, 1971, 17(4), 495-500.

[2]. Swennen Q, et al. Effects of dietary protein content and 2-hydroxy-4-methylthiobutanoic acid or DL-methionine supplementation on performance and oxidative status of broiler chickens. Br J Nutr. 2011 Dec;106(12):1845-54. [Content Brief]

[3]. Garlich JD. Response of broilers to DL-methionine hydroxy analog free acid, DL-methionine, and L-methionine. Poult Sci. 1985 Aug;64(8):1541-8. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
H₂O / 1M HCl	1 mM	6.7015 mL	33.5076 mL	67.0151 mL	167.5379 mL
	5 mM	1.3403 mL	6.7015 mL	13.4030 mL	33.5076 mL
	10 mM	0.6702 mL	3.3508 mL	6.7015 mL	16.7538 mL
	15 mM	0.4468 mL	2.2338 mL	4.4677 mL	11.1692 mL
	20 mM	0.3351 mL	1.6754 mL	3.3508 mL	8.3769 mL
	25 mM	0.2681 mL	1.3403 mL	2.6806 mL	6.7015 mL
	30 mM	0.2234 mL	1.1169 mL	2.2338 mL	5.5846 mL
	40 mM	0.1675 mL	0.8377 mL	1.6754 mL	4.1884 mL
	50 mM	0.1340 mL	0.6702 mL	1.3403 mL	3.3508 mL
	60 mM	0.1117 mL	0.5585 mL	1.1169 mL	2.7923 mL
	80 mM	0.0838 mL	0.4188 mL	0.8377 mL	2.0942 mL
	100 mM	0.0670 mL	0.3351 mL	0.6702 mL	1.6754 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Keywords

DL-Methionine

2 Cited Publications

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DL-Methionine

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Publications Citing Use of MedChemExpress (MCE) DL-Methionine

All Parasite Isoforms

Biological Activity

Chemical Information

Publications (2)

Solvent & Solubility

Purity & Documentation

References

Help & FAQs

Complete Stock Solution Preparation Table

DL-Methionine Related Classifications

HY-N0325 Related Classifications