2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. D-Glucose-13C6

D-Glucose-13C6  (Synonyms: Glucose-13C6; D-(+)-Glucose-13C6; Dextrose-13C6)

Cat. No.: HY-B0389A Purity: 99.93%
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Handling Instructions Technical Support

D-Glucose-13C6 is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose-13C6 can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard.

For research use only. We do not sell to patients.

CAS No. : 110187-42-3

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
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Based on 16 publication(s) in Google Scholar

Other Forms of D-Glucose-13C6:

D-Glucose-13C6 Related Antibodies

Top Publications Citing Use of Products

    D-Glucose-13C6 purchased from MedChemExpress. Usage Cited in: Cell Stem Cell. 2023 Aug 3;30(8):1028-1042.e7.  [Abstract]

    Heatmap of sum of abundance of all 13C-labeled glycolytic intermediates and TCA cycle intermediates in 3-mo and 12-mo AT2 cells after [U-13C]-glucose infusion (n = 3 per group).

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    • Biological Activity

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    • References

    • Customer Review

    Description

    D-Glucose-13C6 is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose-13C6 can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard[1][2][3].

    Application

    1. This compound can be used as a tracer.
    2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

    In Vivo

    D-Glucose-13C6 (0.1 g in 25 g carrot medium for eggs or incorporated with 1 g of 99.5% sucrose in 15 mL water for adults) lightly decreases egg hatching rates, larval development, emerged adults, the period and the number of mating in Ceratitis capitata[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Animal Model: Ceratitis capitata [1]
    Dosage: 0.1 g
    Administration: Add into 25 g carrot medium for eggs or incorporated with 1 g of 99.5% sucrose in 15 mL water for adults
    Result: Decreased hatching rate from 85% to 79% and number of emerged adults from 57% to 50.6%, prolonged development time.
    Decreased the number and period of mating lightly for larvae labeled flies, while decreased the period of mating a bit more for adult labeled flies.
    Molecular Weight

    186.11

    Formula

    13C6H12O6
    CAS No.
    Unlabeled CAS
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    O=[13CH][13C@@H]([13C@H]([13C@@H]([13C@@H]([13CH2]O)O)O)O)O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    4°C, protect from light, stored under nitrogen

    *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

    Solvent & Solubility
    In Vitro: 

    H2O : 100 mg/mL (537.32 mM; Need ultrasonic)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 5.3732 mL 26.8658 mL 53.7317 mL
    5 mM 1.0746 mL 5.3732 mL 10.7463 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

    ×
    Volume (start)

    V1

    =
    Concentration (final)

    C2

    ×
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    In Vivo:

    For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  PBS

      Solubility: 100 mg/mL (537.32 mM); Clear solution; Need ultrasonic

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Purity & Documentation

    Purity: 99.93%

    SDS (396 KB)

    COA (247 KB) HNMR (248 KB) RP-HPLC (244 KB) MS (212 KB)

    Handling Instructions (2659 KB)
    References

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 5.3732 mL 26.8658 mL 53.7317 mL 134.3292 mL
    5 mM 1.0746 mL 5.3732 mL 10.7463 mL 26.8658 mL
    10 mM 0.5373 mL 2.6866 mL 5.3732 mL 13.4329 mL
    15 mM 0.3582 mL 1.7911 mL 3.5821 mL 8.9553 mL
    20 mM 0.2687 mL 1.3433 mL 2.6866 mL 6.7165 mL
    25 mM 0.2149 mL 1.0746 mL 2.1493 mL 5.3732 mL
    30 mM 0.1791 mL 0.8955 mL 1.7911 mL 4.4776 mL
    40 mM 0.1343 mL 0.6716 mL 1.3433 mL 3.3582 mL
    50 mM 0.1075 mL 0.5373 mL 1.0746 mL 2.6866 mL
    60 mM 0.0896 mL 0.4478 mL 0.8955 mL 2.2388 mL
    80 mM 0.0672 mL 0.3358 mL 0.6716 mL 1.6791 mL
    100 mM 0.0537 mL 0.2687 mL 0.5373 mL 1.3433 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    D-Glucose-13C6 Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    D-Glucose-13C6110187-42-3Glucose-13C6 D-(+)-Glucose-13C6 Dextrose-13C6Endogenous MetaboliteD-Glucoseisotope-labeledmetabolic tracersynthesis ingredientminimal media reagentinternal standardCeratitis capitataInhibitorinhibitorinhibit

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