Carbonic anhydrase, Bovine erythrocytes
Based on 1 Customer Validation
Carbonic anhydrase, Bovine erythrocytes (EC 4.2.1.1) is ubiquitous zinc-containing metalloenzyme present in prokaryotes and eukaryotes. Carbonic anhydrase can catalyze reversible conversion of carbon dioxide to bicarbonate and protons. Carbonic anhydrase can be used for the research of cancer, glaucoma, obesity and epilepsy.
For research use only. We do not sell to patients.
- CAS No.: 9001-03-0
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Product Information
Molecular Weight:29.0 kDa (Theoretical)
Optimal pH: 7.0-7.5
Isoelectric Point: 6.40 (Theoretical)
Inhibitors:Monovalent anions, Sulfonates, sulfonamides, Imidazole
Instructions
Dissolve lyophilized powder in ice-cold water at a concentration of 0.1 mg/mL and store in an ice bath until use.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
4.2.1.1
≥3000 U/mg soild
The Unit is determined by the electrometric method of Wilbur and Anderson in which the time required (in seconds) for a saturated CO2 solution to lower the pH of 0.02 M Tris-HCl buffer from 8.3 to 6.3 at 0°C is determined. The time without enzyme is recorded as T0; with enzyme, T. A unit of activity = 2(T0 - T) divided by T.
Chemical Information
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CAS No. 9001-03-0
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Appearance Solid
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Color White to off-white
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SMILES
[Carbonic anhydrase, Bovine erythrocytes]
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Synonyms
EC 4.2.1.1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
H2O : ≥ 50 mg/mL
* "≥" means soluble, but saturation unknown.
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: ≥ 20 mg/mL; Clear solution
Purity & Documentation
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Data Sheet (266 KB)
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SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
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Handling Instructions (2659 KB)
References
[1]. Kanchan Aggarwal, et al. In Situ Photoregulation of Carbonic Anhydrase Activity Using Azobenzenesulfonamides. Biochemistry. 2019 Jan 8;58(1):48-53. [Content Brief]
[2]. Vladimir Amirkhanov, et al. Pharmacophores Modeling in Terms of Prediction of Theoretical Physicochemical Properties and Verification by EXPERIMENTAL correlations of Carbacylamidophosphates (CAPh) and Sulfanylamidophosphates (SAPh) Tested as New Carbonic Anhydrase Inhibitors. Mini Rev Med Chem. 2019;19(12):1015-1027. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Carbonic anhydrase, Bovine erythrocytes Related Classifications
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