Carbonic anhydrase (isoenzyme)
Based on 1 Customer Validation
Carbonic anhydrase isoenzyme is an isoform of Carbonic anhydrase (HY-P1775). Carbonic anhydrase isoenzymes are a class of widely distributed metalloenzymes that catalyze the reversible hydration-dehydration reaction of the carbon dioxide-bicarbonate system, and also exhibit acetaldehyde hydration and ester hydrolysis activities. Carbonic anhydrase isoenzyme is associated with epithelial ion transport processes involving sodium, potassium, anions, and ammonia. Carbonic anhydrase isoenzyme can be used in research on cancer, glaucoma, obesity, and epilepsy.
For research use only. We do not sell to patients.
- CAS No.: 9001-03-0
- Molecular Weight:110000.00
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
Carbonic anhydrase isoenzymes differ in their sensitivity to anion and metal inhibitors, with low-activity isoforms showing greater sensitivity to chloride and lower sensitivity to copper than high-activity isoforms[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
EC Number
4.2.1.1
Enzyme Activity
≥3000 U/mg soild
Unit Definition
One Unit is determined by the electrometric method of Wilbur and Anderson (J. Biol. Chem., 176, 147 (1948)), in which the time required (in seconds) for a saturated CO2 solution to lower the pH of 0.02M Tris-HCl buffer from 8.3 to 6.3, at 0-4°C is determined.
Chemical Information
-
CAS No. 9001-03-0
-
Appearance Solid
-
Molecular Weight 110000.00
-
Color White to off-white
-
SMILES
[Carbonic anhydrase (isoenzyme)]
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
-
Data Sheet (268 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)