952494-46-1
952494-46-1
Chemical Structure
Toreforant
Synonym(s): JNJ-38518168
- CAS No.: 952494-46-1
- Formula:C23H32N6
- Molecular Weight:392.54
IUPAC Name: 5-(5,7-dimethyl-1H-benzo[d]imidazol-2-yl)-4-methyl-N-(3-(1-methylpiperidin-4-yl)propyl)pyrimidin-2-amine
InChIKey: FCRFVPZAXGJLPW-UHFFFAOYSA-N
SMILES: CN1CCC(CCCNC2=NC=C(C3=NC4=CC(C)=CC(C)=C4N3)C(C)=N2)CC1
Biological Activity: Toreforant is a potent and selective histamine H4 receptor (H4R) antagonist, with a Ki at the human receptor of 8.4 nM.
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Toreforant | 97.01% | Toreforant is a potent and selective histamine H4 receptor (H4R) antagonist, with a Ki at the human receptor of 8.4 nM. | ||||||||||||||||||||
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