2. GPCR/G Protein
  3. GLP Receptor
  4. MS012

MS012 is a selective GLP inhibitor (IC50=7 nM). MS012 can be used in research of GLP dysregulation, including cancer, inflammatory diseases, and neuroregenerative disorders.

For research use only. We do not sell to patients.

MS012

MS012 Chemical Structure

CAS No. : 2089617-83-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
1 mg In-stock
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

MS012 Related Antibodies

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Description

MS012 is a selective GLP inhibitor (IC50=7 nM). MS012 can be used in research of GLP dysregulation, including cancer, inflammatory diseases, and neuroregenerative disorders[1].

IC50 & Target

IC50: 7 nM (GLP)[1].
Molecular Weight

401.55

Formula

C22H35N5O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

COC1=CC2=NC(NCCCCCC)=NC(NC3CCN(CC3)C)=C2C=C1OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (124.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4904 mL 12.4517 mL 24.9035 mL
5 mM 0.4981 mL 2.4903 mL 4.9807 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.9%

SDS (251 KB)

COA (246 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4903 mL 12.4517 mL 24.9035 mL 62.2587 mL
5 mM 0.4981 mL 2.4903 mL 4.9807 mL 12.4517 mL
10 mM 0.2490 mL 1.2452 mL 2.4903 mL 6.2259 mL
15 mM 0.1660 mL 0.8301 mL 1.6602 mL 4.1506 mL
20 mM 0.1245 mL 0.6226 mL 1.2452 mL 3.1129 mL
25 mM 0.0996 mL 0.4981 mL 0.9961 mL 2.4903 mL
30 mM 0.0830 mL 0.4151 mL 0.8301 mL 2.0753 mL
40 mM 0.0623 mL 0.3113 mL 0.6226 mL 1.5565 mL
50 mM 0.0498 mL 0.2490 mL 0.4981 mL 1.2452 mL
60 mM 0.0415 mL 0.2075 mL 0.4151 mL 1.0376 mL
80 mM 0.0311 mL 0.1556 mL 0.3113 mL 0.7782 mL
100 mM 0.0249 mL 0.1245 mL 0.2490 mL 0.6226 mL
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MS012 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MS0122089617-83-2MS 012MS-012GLP Receptorcancerinflammationneuroregenerative disordersInhibitorinhibitorinhibit

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