2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor
  4. Seliforant

Seliforant  (Synonyms: SENS-111)

Cat. No.: HY-109074 Purity: ≥95.0%
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Seliforant (SENS-111) is a selective and orally histamine H4 receptor antagonist.

For research use only. We do not sell to patients.

Seliforant Chemical Structure

Seliforant Chemical Structure

CAS No. : 1164115-89-2

Size Price Stock Quantity
5 mg USD 250 In-stock
10 mg USD 380 In-stock
25 mg USD 750 In-stock
50 mg USD 1200 In-stock
100 mg USD 1800 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Seliforant (SENS-111) is a selective and orally histamine H4 receptor antagonist.

Molecular Weight

235.33

Formula

C12H21N5
CAS No.
Appearance

Oil

Color

Light brown to brown

SMILES

CNC1CN(C2=NC(CC(C)C)=NC(N)=C2)C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (424.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2494 mL 21.2468 mL 42.4935 mL
5 mM 0.8499 mL 4.2494 mL 8.4987 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.2494 mL 21.2468 mL 42.4935 mL 106.2338 mL
5 mM 0.8499 mL 4.2494 mL 8.4987 mL 21.2468 mL
10 mM 0.4249 mL 2.1247 mL 4.2494 mL 10.6234 mL
15 mM 0.2833 mL 1.4165 mL 2.8329 mL 7.0823 mL
20 mM 0.2125 mL 1.0623 mL 2.1247 mL 5.3117 mL
25 mM 0.1700 mL 0.8499 mL 1.6997 mL 4.2494 mL
30 mM 0.1416 mL 0.7082 mL 1.4165 mL 3.5411 mL
40 mM 0.1062 mL 0.5312 mL 1.0623 mL 2.6558 mL
50 mM 0.0850 mL 0.4249 mL 0.8499 mL 2.1247 mL
60 mM 0.0708 mL 0.3541 mL 0.7082 mL 1.7706 mL
80 mM 0.0531 mL 0.2656 mL 0.5312 mL 1.3279 mL
100 mM 0.0425 mL 0.2125 mL 0.4249 mL 1.0623 mL
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Seliforant Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Seliforant1164115-89-2SENS-111SENS111SENS 111Histamine ReceptorInhibitorinhibitorinhibit

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