1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. Histamine Receptor
  4. Histamine Receptor Isoform

Histamine Receptor


Histamine Receptor Related Products (203):

Cat. No. Product Name Effect Purity
  • HY-B1204
    Activator 99.99%
    Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
  • HY-12532
    Antagonist 99.62%
    Astemizole (R 43512), a second-generation antihistamine drug to diminish allergic symptoms with a long duration of action, is a histamine H1-receptor antagonist, with an IC50 of 4 nM.
  • HY-N0054
    Inhibitor 99.95%
    Osthole (Osthol) is a natural antihistamine alternative.
  • HY-B0725
    Doxepin Hydrochloride
    Antagonist 99.84%
    Doxepin hydrochloride is an orally active tricyclic antidepressant agent.
  • HY-14289
    Modulator ≥98.0%
    Cimetidine (SKF-92334) is an orally active and inverse histamine H2 receptor antagonist with a Ki of 0.6 μM.
  • HY-12537
    Peptide 401
    Peptide 401, a potent mast cell degranulating factor from bee venom, suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, and 5-HT).
  • HY-105173
    Teverelix (EP 24332) is a GnRH antagonist.
  • HY-B0188A
    Mianserin hydrochloride
    Inhibitor 99.87%
    Mianserin hydrochloride (Org GB 94) is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant.
  • HY-B0781
    Promethazine hydrochloride
    Antagonist ≥98.0%
    Promethazine hydrochloride is the first-generation antihistamine; strong antagonist of the H1 receptor and moderate mACh receptor antagonist, moderate affinity for 5-HT2A, 5-HT2C, D2 and α1-adrenergic receptors.
  • HY-B0286A
    Chlorpheniramine maleate
    Antagonist 99.90%
    Chlorpheniramine maleate is an histamine H1 receptor antagonist with IC50 of 12 nM.
  • HY-W010841
    Levocetirizine dihydrochloride
    Antagonist 99.56%
    Levocetirizine dihydrochloride ((R)-Cetirizine dihydrochloride) is a third-generation peripheral H1-receptor antagonist.
  • HY-B1395
    Mecamylamine hydrochloride
    Inhibitor ≥98.0%
    Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist.
  • HY-B1281
    Mepyramine maleate
    Antagonist 99.96%
    Mepyramine maleate, a first generation antihistamine, is an antagonist of histamine H1 receptor, with Kds of 0.8 nM, 5200 nM and >3000 nM for H1, H2, and H3 receptor, respectively, and a pKd of 9.4 for H1 receptor.
  • HY-B0548A
    Hydroxyzine dihydrochloride
    Antagonist 99.96%
    Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine H1-receptor and serotonin antagonist.
  • HY-A0129
    Histamine phosphate
    Agonist 99.99%
    Histamine (phosphate) diphosphate is a potent agonist of histamine receptors and vasodilator.
  • HY-B0281A
    Ranitidine hydrochloride
    Antagonist ≥98.0%
    Ranitidine hydrochloride is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion.
  • HY-B0377
    Antagonist 99.26%
    Famotidine (MK-208) is a competitive histamine H2-receptor antagonist.
  • HY-14270
    Inhibitor 98.07%
    Lodoxamide (U-42585E free acid) is an antiallergic compound acting as a mast-cell stabilizer for the treatment of asthma and allergic conjunctivitis.
  • HY-B0157A
    Ketotifen fumarate
    Inhibitor 99.92%
    Ketotifen (HC 20-511) fumarate is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer.
  • HY-19705B
    Adriforant hydrochloride
    Antagonist ≥98.0%
    Adriforant hydrochloride (PF-3893787 hydrochloride) is a novel histamine H4 receptor antagonist binding affinity (Ki=2.4 nM) and is also a functional (Ki=1.56 nM) antagonist.