Urea-13C,15N2
Based on 1 Customer Validation
Urea-13C,15N2 is the 13C and 15N labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms. A potent emollient and keratolytic agent. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
For research use only. We do not sell to patients.
- Purity: 99.95%
- CAS No.: 58069-83-3
- Formula: 13CH415N2O
- Molecular Weight:63.03
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 58069-83-3
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Unlabeled Cas 57-13-6
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Appearance Solid
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Molecular Weight 63.03
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Formula 13CH415N2O
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Color White to off-white
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SMILES
[15NH2][13C]([15NH2])=O
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Synonyms
Carbonyl diamide-13C,15N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 200 mg/mL (3173.09 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Bennion BJ, et al. The molecular basis for the chemical denaturation of proteins by urea. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5142-7. [Content Brief]
[3]. Pan M, et al. Urea: a comprehensive review of the clinical literature. Dermatol Online J. 2013 Nov 1519(11):20392.Wang H, et al. Urea. Subcell Biochem. 201473:7-29. [Content Brief]
[4]. Wang H, et al. Urea. Subcell Biochem. 201473:7-29. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 15.8655 mL | 79.3273 mL | 158.6546 mL | 396.6365 mL |
| 5 mM | 3.1731 mL | 15.8655 mL | 31.7309 mL | 79.3273 mL | |
| 10 mM | 1.5865 mL | 7.9327 mL | 15.8655 mL | 39.6637 mL | |
| 15 mM | 1.0577 mL | 5.2885 mL | 10.5770 mL | 26.4424 mL | |
| 20 mM | 0.7933 mL | 3.9664 mL | 7.9327 mL | 19.8318 mL | |
| 25 mM | 0.6346 mL | 3.1731 mL | 6.3462 mL | 15.8655 mL | |
| 30 mM | 0.5288 mL | 2.6442 mL | 5.2885 mL | 13.2212 mL | |
| 40 mM | 0.3966 mL | 1.9832 mL | 3.9664 mL | 9.9159 mL | |
| 50 mM | 0.3173 mL | 1.5865 mL | 3.1731 mL | 7.9327 mL | |
| 60 mM | 0.2644 mL | 1.3221 mL | 2.6442 mL | 6.6106 mL | |
| 80 mM | 0.1983 mL | 0.9916 mL | 1.9832 mL | 4.9580 mL | |
| 100 mM | 0.1587 mL | 0.7933 mL | 1.5865 mL | 3.9664 mL |
Urea-13C,15N2 Related Classifications
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