Urea-¹³C,¹⁵N₂

Name: Urea- 13 C, 15 N 2
Brand: MedChemExpress
SKU: HY-Y0271S2
Rating: 4.5 (1 reviews)

Cat. No.: HY-Y0271S2 Purity: 99.10%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Urea-¹³C,¹⁵N₂ is the ¹³C and ¹⁵N labeled Urea[1]. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

For research use only. We do not sell to patients.

Urea-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub> Chemical Structure

Urea-¹³C,¹⁵N₂ Chemical Structure

CAS No. : 58069-83-3

Size	Price	Stock	Quantity
1 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 190	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 310	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Urea-¹³C,¹⁵N₂:

Urea In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

63.03

Formula

¹³CH₄¹⁵N₂O

CAS No.

58069-83-3

Appearance

Solid

Color

White to off-white

SMILES

[15NH2][13C]([15NH2])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL (3966.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	15.8655 mL	79.3273 mL	158.6546 mL
5 mM	3.1731 mL	15.8655 mL	31.7309 mL
10 mM	1.5865 mL	7.9327 mL	15.8655 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.10%

Select Batch:

Data Sheet (272 KB) SDS (393 KB)

COA (246 KB) HNMR (126 KB) RP-HPLC (76 KB) MS (71 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Bennion BJ, et al. The molecular basis for the chemical denaturation of proteins by urea. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5142-7. [Content Brief]

[3]. Pan M, et al. Urea: a comprehensive review of the clinical literature. Dermatol Online J. 2013 Nov 1519(11):20392.Wang H, et al. Urea. Subcell Biochem. 201473:7-29. [Content Brief]

[4]. Wang H, et al. Urea. Subcell Biochem. 201473:7-29. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	15.8655 mL	79.3273 mL	158.6546 mL	396.6365 mL
	5 mM	3.1731 mL	15.8655 mL	31.7309 mL	79.3273 mL
	10 mM	1.5865 mL	7.9327 mL	15.8655 mL	39.6637 mL
	15 mM	1.0577 mL	5.2885 mL	10.5770 mL	26.4424 mL
	20 mM	0.7933 mL	3.9664 mL	7.9327 mL	19.8318 mL
	25 mM	0.6346 mL	3.1731 mL	6.3462 mL	15.8655 mL
	30 mM	0.5288 mL	2.6442 mL	5.2885 mL	13.2212 mL
	40 mM	0.3966 mL	1.9832 mL	3.9664 mL	9.9159 mL
	50 mM	0.3173 mL	1.5865 mL	3.1731 mL	7.9327 mL
	60 mM	0.2644 mL	1.3221 mL	2.6442 mL	6.6106 mL
	80 mM	0.1983 mL	0.9916 mL	1.9832 mL	4.9580 mL
	100 mM	0.1587 mL	0.7933 mL	1.5865 mL	3.9664 mL