1. Neuronal Signaling
  2. Cholinesterase (ChE)
  3. Choline-d4 chloride

Choline-d4 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.

For research use only. We do not sell to patients.

Choline-d<sub>4</sub> chloride Chemical Structure

Choline-d4 chloride Chemical Structure

CAS No. : 285979-70-6

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5 mg USD 80 In-stock
10 mg USD 130 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Choline-d4 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

143.65

Formula

C5H10D4ClNO

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])(O)C([N+](C)(C)C)([2H])[2H].[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (696.14 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.9614 mL 34.8068 mL 69.6136 mL
5 mM 1.3923 mL 6.9614 mL 13.9227 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥99.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.9614 mL 34.8068 mL 69.6136 mL 174.0341 mL
5 mM 1.3923 mL 6.9614 mL 13.9227 mL 34.8068 mL
10 mM 0.6961 mL 3.4807 mL 6.9614 mL 17.4034 mL
15 mM 0.4641 mL 2.3205 mL 4.6409 mL 11.6023 mL
20 mM 0.3481 mL 1.7403 mL 3.4807 mL 8.7017 mL
25 mM 0.2785 mL 1.3923 mL 2.7845 mL 6.9614 mL
30 mM 0.2320 mL 1.1602 mL 2.3205 mL 5.8011 mL
40 mM 0.1740 mL 0.8702 mL 1.7403 mL 4.3509 mL
50 mM 0.1392 mL 0.6961 mL 1.3923 mL 3.4807 mL
60 mM 0.1160 mL 0.5801 mL 1.1602 mL 2.9006 mL
80 mM 0.0870 mL 0.4351 mL 0.8702 mL 2.1754 mL
100 mM 0.0696 mL 0.3481 mL 0.6961 mL 1.7403 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Choline-d4 chloride Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Choline-d4 chloride
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