Choline-d4 chloride
Based on 1 publication(s) in Google Scholar
Choline-d4 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
For research use only. We do not sell to patients.
- Purity: 99.90%
- CAS No.: 285979-70-6
- Formula: C5H10D4ClNO
- Molecular Weight:143.65
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) Choline-d4 chloride
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 285979-70-6
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Unlabeled Cas 67-48-1
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Appearance Solid
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Molecular Weight 143.65
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Formula C5H10D4ClNO
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Color White to off-white
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SMILES
[2H]C([2H])(O)C([N+](C)(C)C)([2H])[2H].[Cl-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Biochem Pharmacol
Diversity of human choline transporters: substrate specificity, kinetic properties, and inhibitor sensitivity. [Abstract]2025 Dec;242(Pt 2):117343. PMID: 40972734
Solvent & Solubility
H2O : ≥ 100 mg/mL (696.14 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.9614 mL | 34.8068 mL | 69.6136 mL | 174.0341 mL |
| 5 mM | 1.3923 mL | 6.9614 mL | 13.9227 mL | 34.8068 mL | |
| 10 mM | 0.6961 mL | 3.4807 mL | 6.9614 mL | 17.4034 mL | |
| 15 mM | 0.4641 mL | 2.3205 mL | 4.6409 mL | 11.6023 mL | |
| 20 mM | 0.3481 mL | 1.7403 mL | 3.4807 mL | 8.7017 mL | |
| 25 mM | 0.2785 mL | 1.3923 mL | 2.7845 mL | 6.9614 mL | |
| 30 mM | 0.2320 mL | 1.1602 mL | 2.3205 mL | 5.8011 mL | |
| 40 mM | 0.1740 mL | 0.8702 mL | 1.7403 mL | 4.3509 mL | |
| 50 mM | 0.1392 mL | 0.6961 mL | 1.3923 mL | 3.4807 mL | |
| 60 mM | 0.1160 mL | 0.5801 mL | 1.1602 mL | 2.9006 mL | |
| 80 mM | 0.0870 mL | 0.4351 mL | 0.8702 mL | 2.1754 mL | |
| 100 mM | 0.0696 mL | 0.3481 mL | 0.6961 mL | 1.7403 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.