2. Signaling Pathways
  3. Stem Cell/Wnt
  4. PKG

PKG

 
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-P1292
    PKG inhibitor peptide
    		99.91%
    PKG inhibitor peptide is an ATP-competitive inhibitor of cGMP-dependent protein kinase (PKG), with a Ki of 86 μM.
    PKG inhibitor peptide
  • HY-112197
    PKG drug G1
    		99.63%
    PKG agent G1 targets C42 of PKG Iα. PKG agent G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Iα-independent mechanism.
    PKG drug G1
  • HY-P1556A
    Vasonatrin Peptide (VNP) (TFA)
    		98.79%
    Vasonatrin Peptide (VNP) TFA is a chimera of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP). Vasonatrin peptide TFA possesses the venodilating actions of CNP, the natriuretic actions of ANP, and unique arterial vasodilating actions not associated with either ANP or CNP. Vasonatrin Peptide TFA protects the diabetic heart against ischemia-reperfusion injury by inhibiting ER stress via the cGMP-PKG signaling pathway.
    Vasonatrin Peptide (VNP) (TFA)
  • HY-P1292A
    PKG inhibitor peptide TFA
    PKG inhibitor peptide TFA is an ATP-competitive inhibitor of cGMP-dependent protein kinase (PKG), with a Ki of 86 μM.
    PKG inhibitor peptide TFA
  • HY-P1556
    Vasonatrin Peptide (VNP)
    Vasonatrin Peptide (VNP) is a chimera of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP). Vasonatrin peptide possesses the venodilating actions of CNP, the natriuretic actions of ANP, and unique arterial vasodilating actions not associated with either ANP or CNP. Vasonatrin Peptide protects the diabetic heart against ischemia-reperfusion injury by inhibiting ER stress via the cGMP-PKG signaling pathway.
    Vasonatrin Peptide (VNP)
  • HY-110221
    Rp-8-pCPT-cGMPS sodium
    		Inhibitor
    Rp-8-pCPT-cGMPS sodium is the sodium salt form of Rp-8-pCPT-cGMPS. Rp-8-pCPT-cGMPS is an inhibitor for cGMP-dependent protein kinase (cGK). Rp-8-pCPT-cGMPS sodium is an agonist for cyclic nucleotide-gated (CNG) channels in a voltage-dependent manner.
    Rp-8-pCPT-cGMPS sodium
  • HY-P10036
    G-Subtide
    G-Subtide is a G-substrate peptide localized in Purkinje cells of the cerebellum. G-Subtide has little activity distinct from background and is a preferentially phosphorylated peptide substrate of recombinant PfPKG2 protein.
    G-Subtide
  • HY-151203
    PKG1α activator 3
    PKG1α activator 3 is a PKG1α activator (EC50 basal/partial=13/0.52 μM). PKG1α activator 3 shows anti-proliferative effects to smooth muscle cell, and can be used in cardiovascular disease research.
    PKG1α activator 3
  • HY-P1561
    PKG Substrate
    		98.05%
    PKG Substrate is a selective substrate for cGMP-dependent protein kinase (PKG).
    PKG Substrate
  • HY-155106
    SMA4
    SMA4 is a selective PKG1α activator with basal EC50 value of 29 μM. SMA4 facilitates phosphorylation of the known PKG1 substrate, vasodilator-stimulated phosphoprotein (VASP), and inhibits human pulmonary arterial smooth muscle cells (hPASMC) proliferation. SMA4 can be used for cardiovascular disease research.
    SMA4
Cat. No. Product Name / Synonyms Application Reactivity