Rp-8-pCPT-cGMPS sodium
Based on 1 publication(s) in Google Scholar
Rp-8-pCPT-cGMPS sodium is the sodium salt form of Rp-8-pCPT-cGMPS. Rp-8-pCPT-cGMPS is an inhibitor for cGMP-dependent protein kinase (cGK). Rp-8-pCPT-cGMPS sodium is an agonist for cyclic nucleotide-gated (CNG) channels in a voltage-dependent manner.
For research use only. We do not sell to patients.
- Purity: 99.9%
- CAS No.: 208445-07-2
- Formula: C16H14ClN5NaO6PS2
- Molecular Weight:525.86
-
Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Rp-8-pCPT-cGMPS sodium
More
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Bone cancer pain induced by tumor cell implantation (TCI) in Sprague-Dawley rats[1].
-
Dosage:0.5 mmol/L, 20 μL
-
Administration:intrathecally, once a day for 3 days
-
Result:Delayed and suppressed TCI-induced thermal hyperalgesia and mechanical allodynia.
Chemical Information
-
CAS No. 208445-07-2
-
Appearance Solid
-
Molecular Weight 525.86
-
Formula C16H14ClN5NaO6PS2
-
Color White to off-white
-
SMILES
O[C@H]1[C@](O[C@@](CO2)([H])[C@@]1([H])O[P@@]2(S[Na])=O)([H])N3C(NC(N)=NC4=O)=C4N=C3SC(C=C5)=CC=C5Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Sci Rep
2025 Oct 16;15(1):36270. PMID: 41102391
Purity & Documentation
-
Data Sheet (276 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
[1]. Liu S, et al., cGMP and cGMP-dependent protein kinase I pathway in dorsal root ganglia contributes to bone cancer pain in rats. Spine (Phila Pa 1976). 2014 Sep 1;39(19):1533-41. [Content Brief]
[2]. Wei JY, et al., Substituted cGMP analogs can act as selective agonists of the rod photoreceptor cGMP-gated cation channel. J Mol Neurosci. 1998 Feb;10(1):53-64. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Rp-8-pCPT-cGMPS sodium Related Classifications
HY-110221 Related Classifications
Powered by Bioz