PKG inhibitor peptide TFA
Based on 2 publication(s) in Google Scholar
PKG inhibitor peptide TFA is an ATP-competitive inhibitor of cGMP-dependent protein kinase (PKG), with a Ki of 86 μM.
For research use only. We do not sell to patients.
- Formula: C40H75F3N18O12
- Molecular Weight:1057.13
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) PKG inhibitor peptide TFA
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Biological Activity
Ki: 86 μM (PKG)[1]
Summary of experiments showing that intracellular dialysis of postsynaptic cells with PKG inhibitor PKG inhibitor peptide TFA (1 mM) failed to alter the induction of long-term depression (CCh-LTD)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 1057.13
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Formula C40H75F3N18O12
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Sequence
Arg-Lys-Arg-Ala-Arg-Lys-Glu
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Sequence Shortening
RKRARKE
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Nature
2025 Sep;645(8079):244-253. PMID: 40562926 -
Oncogene
LAMP5 modulates IRF4 stability and nuclear transport: a critical mechanism in myeloma progression and therapy. [Abstract]2025 Jul 28. PMID: 40721659
Purity & Documentation
References
[1]. Bhatnagar D, et al. Synthetic peptide analogues differentially alter the binding affinities of cyclic nucleotide dependent protein kinases for nucleotide substrates. Biochemistry. 1988 Mar 22;27(6):1988-94. [Content Brief]
[2]. Chiung-Chun Huang, et al. Activation of muscarinic acetylcholine receptors induces a nitric oxide-dependent long-term depression in rat medial prefrontal cortex. Cereb Cortex. 2010 Apr;20(4):982-96. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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