U 92163
U 92163 is an HIV-2 protease inhibitor. It is a synthetic peptidomimetic transition-state analog. U 92163 binds in an extended conformation along the length of the enzyme's binding cleft, and forms hydrogen bonds with the catalytic aspartate pair and other protease residues to block enzyme activity. U 92163 can be used in research on acquired immunodeficiency syndrome (AIDS).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 149607-21-6
- Formule: C34H51N5O5
- Masse moléculaire:609.81
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
U 92163 plays a role in the crystalline HIV-2 protease/inhibitor complex by occupying the substrate-binding pocket of the protease binding cleft, forming a hydrogen bond network with the catalytic site Asp25/Asp125 and side chain residues, and inducing protein conformational changes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 149607-21-6
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Masse moléculaire 609.81
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Formule C34H51N5O5
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SMILES
C(N[C@H](C(N[C@@H](CC1CCCCC1)[C@H](C[C@H](C(NCC(C)(C)C)=O)[C@H](C)C)O)=O)CC(N)=O)(=O)C2=NC3=C(C=C2)C=CC=C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
U 92163 Related Classifications
HY-187623 Related Classifications
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