3054-47-5
Chemical Structure
S-Acetylglutathione
- CAS No.: 3054-47-5
- Formula:C12H19N3O7S
- Molecular Weight:349.36
IUPAC Name: N5-((R)-3-(acetylthio)-1-((carboxymethyl)amino)-1-oxopropan-2-yl)-L-glutamine
InChIKey: FVRWSIPJNWXCEO-YUMQZZPRSA-N
SMILES: O=C(O)CNC([C@H](CSC(C)=O)NC(CC[C@@H](C(O)=O)N)=O)=O
Biological Activity: S-Acetylglutathione is a glutathione derivative and intracellular glutathione supplement that bypasses glutathione synthetase deficiency through intracellular thioesterase conversion, exhibits higher blood stability than glutathione, and selectively induces apoptosis in lymphoma and malignant cells by inducing oxidative stress (apoptosis). S-Acetylglutathione can be used in research on glutathione synthetase deficiency, herpes simplex virus type 1 infection, murine AIDS, lymphoma, and malignant tumors[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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S-Acetylglutathione | 98.57% | S-Acetylglutathione is a glutathione derivative and intracellular glutathione supplement that bypasses glutathione synthetase deficiency through intracellular thioesterase conversion, exhibits higher blood stability than glutathione, and selectively induces apoptosis in lymphoma and malignant cells by inducing oxidative stress (apoptosis). S-Acetylglutathione can be used in research on glutathione synthetase deficiency, herpes simplex virus type 1 infection, murine AIDS, lymphoma, and malignant tumors. | ||||||||||||||||||||
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References
- [1]. Okun JG, et al. S-Acetylglutathione normalizes intracellular glutathione content in cultured fibroblasts from patients with glutathione synthetase deficiency. Journal of inherited metabolic disease. 2004;27(6):783-6. [Content Brief]
- [2]. Vogel JU, et al. Effects of S-acetylglutathione in cell and animal model of herpes simplex virus type 1 infection. Medical microbiology and immunology. 2005 Jan;194(1-2):55-9. [Content Brief]
- [3]. Fraternale A, et al. Inhibition of murine AIDS by pro-glutathione (GSH) molecules. Antiviral research. 2008 Feb;77(2):120-7.
- [4]. Locigno R, et al. S-acetyl-glutathione selectively induces apoptosis in human lymphoma cells through a GSH-independent mechanism. International journal of oncology. 2002 Jan;20(1):69-75.
- [5]. Donnerstag B, et al. Reduced glutathione and S-acetylglutathione as selective apoptosis-inducing agents in cancer therapy. Cancer letters. 1996 Dec 20;110(1-2):63-70. [Content Brief]
