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PLGA (50:50)

(Synonyms: poly(lactic-co-glycolic acid) (50:50))
32 Cited Publications
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Based on 32 publication(s) in Google Scholar

PLGA (50:50) (poly(lactic-co-glycolic acid) (50:50)) is a copolymer of poly lactic acid (PLA) and poly glycolic acid (PGA) which can be used to fabricate devices for drug delivery and tissue engineering applications.

For research use only. We do not sell to patients.

  • Purity: 99.41%
  • CAS No.: 34346-01-5
  • Formula: (C3H6O3)n.(C2H4O3)n
  • Molecular Weight:10000-20000
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • PLGA (50:50) Chemical Structure
    PLGA (50:50) Chemical Structure
  • Experimental Validation Results for PLGA (50:50)
  • Experimental Validation Results for PLGA (50:50)
  • Experimental Validation Results for PLGA (50:50)
  • Experimental Validation Results for PLGA (50:50)
  • Experimental Validation Results for PLGA (50:50)
CAS No.: 34346-01-5
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609-228-6898
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • PLGA (50:50) Chemical Structure
    PLGA (50:50) Chemical Structure
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    PLGA (50:50) purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Mar;12(10):e2412799. [Abstract]

    Customer Validation
     Hydrodynamic sizes of PLGA (10 mg/mL; 4 h) cores, MΦ NPs, OLA@MΦ NPs, and OLA@MΦ NPs-2 (OLA@MΦ NPs isolated from cp-OLA@MΦ NPs) were measured (n = 3).

  • 1/16

    PLGA (50:50) purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Mar;12(10):e2412799. [Abstract]

    Customer Validation
     PLGA (10 mg/mL; 4 h). TEM images of PLGA cores and OLA@MΦ NPs-2 were obtained.

  • 1/16

    PLGA (50:50) purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Mar;12(10):e2412799. [Abstract]

    Customer Validation
     PLGA (10 mg/mL; 4 h). Western blot analysis of IL-1R, IL-6R, TNFR, and TLR4 in PLGA cores, MΦ NPs, OLA@MΦ NPs, and OLA@MΦ NPs-2.

  • 1/16

    PLGA (50:50) purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2020 Sep:129:110371. [Abstract]

    Customer Validation
     Immunofluorescence staining displays weaker Bcl-2 fluorescence intensity in lung cancer cells incubated with RBCm-Obatoclax Mesylate (OM)/PLGA, accompanied with stronger expression of pro-apoptotic signal Bax in comparison to the Con group.

  • 1/16

    PLGA (50:50) purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2020 Sep:129:110371. [Abstract]

    Customer Validation
     Bcl-2 and Bcl-xl protein expression levels are restrained in A549 and H1975 cells treated with RBCm-OM/PLGA; however, Bax, cleaved Caspase-3, Caspase-9 and PARP are up-regulated following RBCm-OM/PLGA incubation. Also, free Obatoclax Mesylate (OM) does not influence the expression change of all these proteins.

  • PLGA (50:50)