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SM-102 

Cat. No.: HY-134541 Purity: ≥98.0%
Handling Instructions

SM-102 is an ionizable amino lipid that can be used for the formation of lipid nanoparticles (LNPs). SM-102 has the potential for development of lipid nanoparticles for delivery of mRNA-based vaccines.

For research use only. We do not sell to patients.

SM-102 Chemical Structure

SM-102 Chemical Structure

CAS No. : 2089251-47-6

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Free Sample (0.5-1 mg)   Apply Now  
25 mg USD 650 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1150 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1900 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

SM-102 is an ionizable amino lipid that can be used for the formation of lipid nanoparticles (LNPs)[1]. SM-102 has the potential for development of lipid nanoparticles for delivery of mRNA-based vaccines[2].

Molecular Weight

710.17

Formula

C₄₄H₈₇NO₅

CAS No.
SMILES

O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCO)CCCCCC(OCCCCCCCCCCC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (140.81 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4081 mL 7.0406 mL 14.0811 mL
5 mM 0.2816 mL 1.4081 mL 2.8162 mL
10 mM 0.1408 mL 0.7041 mL 1.4081 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (3.52 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (3.52 mM); Suspended solution; Need ultrasonic

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (3.52 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

SM-102SM102SM 102OthersmRNAdeliverylipid nanoparticlevaccinesCOVID-19Inhibitorinhibitorinhibit

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Product Name:
SM-102
Cat. No.:
HY-134541
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