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  2. Cationic Lipids
  3. C12-200

C12-200 

Cat. No.: HY-145405 Purity: ≥98.0%
Handling Instructions

C12-200 is a benchmark ionizable cationic lipidoid along with helper lipids. C12-200 is commonly used for mRNA delivery.

For research use only. We do not sell to patients.

C12-200 Chemical Structure

C12-200 Chemical Structure

CAS No. : 1220890-25-4

Size Price Stock Quantity
10 mg USD 380 In-stock
Estimated Time of Arrival: December 31
25 mg USD 800 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1280 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2100 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

C12-200 is a benchmark ionizable cationic lipidoid along with helper lipids. C12-200 is commonly used for mRNA delivery[1][2].

Molecular Weight

1136.93

Formula

C70H145N5O5

CAS No.
SMILES

OC(CCCCCCCCCC)CN(CCN(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O)CCN1CCN(CCN(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O)CC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (87.96 mM; Need ultrasonic)

Ethanol : 100 mg/mL (87.96 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8796 mL 4.3978 mL 8.7956 mL
5 mM 0.1759 mL 0.8796 mL 1.7591 mL
10 mM 0.0880 mL 0.4398 mL 0.8796 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (2.20 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (2.20 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (2.20 mM); Clear solution

  • 4.

    Add each solvent one by one:  10% EtOH    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (2.20 mM); Clear solution

  • 5.

    Add each solvent one by one:  10% EtOH    90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (2.20 mM); Suspended solution; Need ultrasonic

  • 6.

    Add each solvent one by one:  10% EtOH    90% corn oil

    Solubility: ≥ 2.5 mg/mL (2.20 mM); Clear solution

*All of the co-solvents are available by MCE.
References

Purity: ≥98.0%

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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
C12-200
Cat. No.:
HY-145405
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