92451-01-9
92451-01-9
Chemical Structure
m-PEG5000-NHS ester
Synonym(s): mPEG5000-SC; mPEG5000-Succinimidyl ester
- CAS No.: 92451-01-9
- Formula:(C2H4O)nC7H9NO5
- Molecular Weight:5000 (Average)
SMILES: COCCOCC(ON1C(CCC1=O)=O)=O.[n]
Biological Activity: m-PEG5000-NHS ester (mPEG5000-SC) is a pegylation reagent that targets the primary amino groups of branched polyethyleneimine on gold nanoparticles. m-PEG1000-NHS ester covalently links its PEG moiety to target amino groups via amine-mediated coupling chemistry. m-PEG1000-NHS ester helps improve the biocompatibility of modified gold nanoparticles used as CT contrast agents and prolongs their blood circulation time.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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m-PEG5000-NHS ester | 95.0% | m-PEG5000-NHS ester (mPEG5000-SC) is a pegylation reagent that targets the primary amino groups of branched polyethyleneimine on gold nanoparticles. m-PEG1000-NHS ester covalently links its PEG moiety to target amino groups via amine-mediated coupling chemistry. m-PEG1000-NHS ester helps improve the biocompatibility of modified gold nanoparticles used as CT contrast agents and prolongs their blood circulation time. | ||||||||||||||||||||
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m-PEG1000-NHS ester | 80.0% | m-PEG1000-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects. | ||||||||||||||||||||
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m-PEG350-NHS ester | 90.0% | m-PEG350-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects. | ||||||||||||||||||||
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m-PEG550-NHS ester | m-PEG550-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects. | |||||||||||||||||||||
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m-PEG20000-NHS ester | 98.0% | m-PEG20000-NHS ester (mPEG20000-SC) is a pegylation reagent that targets the primary amino groups of branched polyethyleneimine on gold nanoparticles. m-PEG1000-NHS ester covalently links its PEG moiety to target amino groups via amine-mediated coupling chemistry. m-PEG1000-NHS ester helps improve the biocompatibility of modified gold nanoparticles used as CT contrast agents and prolongs their blood circulation time. | ||||||||||||||||||||
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m-PEG3400-NHS ester | 98.0% | m-PEG3400-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects. | ||||||||||||||||||||
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m-PEG40000-NHS ester | 98.0% | m-PEG-NHS ester (mPEG-SC; mPEG-Succinimidyl ester) (MW 40000) is a polyethylene glycol derivative. m-PEG-NHS ester serves as a modifying agent that reacts with free amino groups on the surface of protein or polypeptide molecules to form stable amide bonds, thereby covalently linking PEG chains to biomacromolecules, improving their antigenicity and immunogenicity, and facilitating the preparation of injectable formulations. | ||||||||||||||||||||
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m-PEG10000-NHS ester | 98.0% | m-PEG10000-NHS ester (mPEG10000-SC) is a pegylation reagent that targets the primary amino groups of branched polyethyleneimine on gold nanoparticles. m-PEG1000-NHS ester covalently links its PEG moiety to target amino groups via amine-mediated coupling chemistry. m-PEG1000-NHS ester helps improve the biocompatibility of modified gold nanoparticles used as CT contrast agents and prolongs their blood circulation time. | ||||||||||||||||||||
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m-PEG2000-NHS ester | 95.89% | m-PEG2000-NHS ester (mPEG2000-SC) is a reagent with both cell adhesion inhibition and peptide conjugation functions. The NHS ester group of m-PEG2000-NHS ester forms stable amide bonds with primary amine-containing molecules (e.g., the N-terminus of MMP-2-cleavable octapeptide) to generate mPEG-peptide intermediates for liposome surface modification. When m-PEG2000-NHS ester is immobilized on a cystamine-modified gold surface, it can construct an in vitro model for cell adhesion kinetic studies, and higher PEG density and thicker layers correlate with lower cell adhesion rates. m-PEG2000-NHS ester can synthesize MMP-2-responsive PEGylated lipid conjugates to achieve MMP-triggered dePEGylation in the tumor microenvironment. m-PEG2000-NHS ester can be used in studies related to colon cancer and other conditions. | ||||||||||||||||||||
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