m-PEG3400-NHS ester
Based on 1 Customer Validation
m-PEG3400-NHS ester (mPEG3400-SC; mPEG3400-Succinimidyl ester) is a polyethylene glycol (PEG)-based biocompatibility-enhancing modifier. m‑PEG3400‑NHS ester enables PEGylation of molecules such as proteins, which reduces the immunogenicity and antigenicity of target molecules, decreases the tendency of protein aggregation, and protects proteins from hydrolysis. m-PEG3400-NHS ester can be used in drug delivery-related research.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 92451-01-9
- Formula: (C2H4O)nC7H9NO5
- Molecular Weight:3400 (Average)
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
In Vitro
m-PEG3400-NHS ester can be coupled to the ApoE-NH2 peptide via NHS ester chemical reaction, and purified ApoE-PEG targeting chains are obtained after dialysis and lyophilization[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 92451-01-9
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Appearance Solid
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Molecular Weight 3400 (Average)
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Formula (C2H4O)nC7H9NO5
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Color White to off-white
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SMILES
COCCOCC(ON1C(CCC1=O)=O)=O.[n]
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Synonyms
mPEG3400-SC; mPEG3400-Succinimidyl ester
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- m-PEG3400-NHS ester
- 92451-01-9
- mPEG3400-SC
- mPEG3400-Succinimidyl ester
- Biochemical Assay Reagents
- Drug Intermediate
- tumor microenvironment-sensitive molecules
- NHS-ester chemistry
- polyethylene glycol
- nanocomposite shell
- glioma
- N
- N'-bis(acryloyl)cystamine
- AAV2 nanocapsules
- apolipoprotein E peptide
- guanidino acrylate
- ApoE-NH2 peptide
- Inhibitor
- inhibitor
- inhibit