MMP7

Isoforms Recommended:	MMP-7

By Targets:	COX (1) Fluorescent Dye (1) MMP (11) Small Interfering RNA (siRNA) (3) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (9) Inflammation/Immunology (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-153563

MMP-7-IN-2

MMP Others

MMP-7-IN-2 (compound 16) is a selective inhibitor of MMP7 with an IC₅₀ value of 16 nM .

MMP-7-IN-2	MMP	Others
MMP-7-IN-2 (compound 16) is a selective inhibitor of *MMP7* with an IC₅₀ value of 16 nM .

HY-151540

MMP-7-IN-1	MMP	Cancer
MMP-7-IN-1 is a potent and selective inhibitor of *MMP-7* over MMP-1, -2, -3, -8, -9, -13 with an IC₅₀ value of 10 nM. MMP-7 is a potential target for diseases including cancer and fibrosis .

HY-RS08551

MMP7 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MMP7 Human Pre-designed siRNA Set A contains three designed siRNAs for MMP7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MMP7 Human Pre-designed siRNA Set A MMP7 Human Pre-designed siRNA Set A

HY-RS08552

Mmp7 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Mmp7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mmp7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Mmp7 Mouse Pre-designed siRNA Set A Mmp7 Mouse Pre-designed siRNA Set A

HY-RS08553

Mmp7 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Mmp7 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mmp7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Mmp7 Rat Pre-designed siRNA Set A Mmp7 Rat Pre-designed siRNA Set A

HY-156430

MMP-7-IN-3	MMP	Cancer
MMP-7-IN-3 is a potent and selective inhibitor of *MMP-7. MMP-7*-IN-3 suppresses kidney fibrosis progression in a mouse model with unilateral ureteral obstruction .

HY-161169

TP0628103

MMP Cancer

TP0628103 (compound 18) is a selective inhibitor of MMP-7, with the IC₅₀ value of 0.17 nM that plays an important role in cancer and fibrosis .

TP0628103	MMP	Cancer
TP0628103 (compound 18) is a selective inhibitor of *MMP*-7, with the IC₅₀ value of 0.17 nM that plays an important role in cancer and fibrosis .

HY-13564

Batimastat 5+ Cited Publications BB94	MMP	Cancer
Batimastat is a potent broad spectrum *MMP* inhibitor with IC₅₀ of 3, 4, 4, 6, and 20 nM for *MMP-1, MMP-2, MMP-9, MMP-7* and *MMP-3*, respectively.

HY-13564A

Batimastat sodium salt BB-94 sodium salt	MMP	Cancer
Batimastat sodium salt is a potent broad spectrum *MMP* inhibitor with IC₅₀ of 3, 4, 4, 6, and 20 nM for *MMP-1, MMP-2, MMP-9, MMP-7* and *MMP-3*, respectively.

HY-131498

MOCAc-PLGL(Dpa)AR	Fluorescent Dye	Others
MOCAc-PLGL(Dpa)AR is a positively charged fluorescent substrate for matrix metalloproteinase-2 (MMP-2) and *MMP-7*. MOCAc-PLGL(Dpa)AR is a substrate of matrilysin, can be cleaved at the peptide bond between the glycine and leucine residues .

HY-119423

MMP Inhibitor II	MMP	Cancer
MMP Inhibitor II (compound 4e) is a potent, reversible pan-MMP inhibitor with IC₅₀ values of 24 nM, 18.4 nM, 30 nM, and 2.7 nM for MMP-1,MMP-3, MMP-7, and MMP-9, respectively .

HY-130076

MMP-2 Inhibitor II	MMP	Cancer
MMP-2 Inhibitor II (compound 2) is a selective *MMP-2* inhibitor. The Kinetic parameters for MMP inhibition are 2.4 μM (MMP-2), 45 μM (MMP-1), and 379 μM (MMP-7), respectively .

HY-N0774

Isofraxidin 1 Publications Verification	COX MMP Toll-like Receptor (TLR)	Inflammation/Immunology
Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits *MMP-7* expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells . Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation .

HY-103444

ARP-100	MMP	Cancer
ARP-100 is a potent and selective matrix metalloproteinase *MMP-2* inhibitor (IC₅₀=12 nM). ARP-100 interacts with S1＇ pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel. ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM) .

HY-12169

Marimastat Maximum Cited Publications 10 Publications Verification BB2516; TA2516	MMP	Cancer
Marimastat (BB2516) is a broad spectrum and orally bioavailable inhibitor of *MMPs, with potent activity against MMP-9 (IC₅₀=3 nM), MMP-1 (IC₅₀=5 nM), MMP-2 (IC₅₀=6 nM), MMP-14 (IC₅₀=9 nM) and MMP-7* (IC₅₀=13 nM), used in the treatment of cancer. Marimastat (BB2516) is an angiogenesis and metastasis inhibitor, which limits the growth and production of blood vessels. As an antimetatstatic agent it prevents malignant cells from breaching the basement membranes .

Cat. No.	Product Name	Type

HY-131498

MOCAc-PLGL(Dpa)AR	Fluorescent Dyes/Probes
MOCAc-PLGL(Dpa)AR is a positively charged fluorescent substrate for matrix metalloproteinase-2 (MMP-2) and *MMP-7*. MOCAc-PLGL(Dpa)AR is a substrate of matrilysin, can be cleaved at the peptide bond between the glycine and leucine residues .

Cat. No.	Product Name	Target	Research Area

HY-153563

MMP-7-IN-2

MMP Others

MMP-7-IN-2 (compound 16) is a selective inhibitor of MMP7 with an IC₅₀ value of 16 nM .

MMP-7-IN-2	MMP	Others
MMP-7-IN-2 (compound 16) is a selective inhibitor of *MMP7* with an IC₅₀ value of 16 nM .

HY-156430

MMP-7-IN-3	MMP	Cancer
MMP-7-IN-3 is a potent and selective inhibitor of *MMP-7. MMP-7*-IN-3 suppresses kidney fibrosis progression in a mouse model with unilateral ureteral obstruction .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0774

Isofraxidin 1 Publications Verification	Structural Classification Monophenols Classification of Application Fields Source classification Coumarins Phenols Phenylpropanoids Acanthopanax senticosus (Rupr. et Maxim.) Harms Plants Inflammation/Immunology Disease Research Fields Araliaceae	COX MMP Toll-like Receptor (TLR)
Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits *MMP-7* expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells . Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation .

Recombinant Proteins Recommended:

MMP-7

Cat. No.	Compare	Product Name	Species	Source

HY-P700574

	MMP-7 Protein, Rat (P. pastoris, His) Matrilysin; Matrin; Matrix metalloproteinase-7; Pump-1 protease; MPSL1; PUMP1	Rat	P. pastoris
	The MMP-7 protein is an enzyme with multifunctional substrate-degrading capabilities, acting on casein, gelatin (types I, III, IV, and V) and fibronectin. As a multifunctional matrix metalloproteinase, MMP-7 contributes to tissue remodeling and renewal, including procollagenase activation, demonstrating its role in the regulation of collagen metabolism. MMP-7 Protein, Rat (P. pastoris, His) is the recombinant rat-derived MMP-7 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of MMP-7 Protein, Rat (P. pastoris, His) is 170 a.a., with molecular weight of 20.9 kDa.


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Cat. No.	Product Name	Application	Reactivity

HY-P81117

MMP7 Antibody Matrilysin; Matrilysin uterine; Matrin; Matrix Metalloproteinase 7; MMP-7; MMP 7; MMP7; MPSL1; PUMP 1; Pump 1 protease; PUMP1; Uterine Matrilysin; Uterine metalloproteinase; MMP7_HUMAN.	WB; ELISA; IHC-P; IHC-F; IF	Human, Mouse(predicted: Rat)
MMP7 Antibody is an unconjugated, approximately 30 kDa, rabbit-derived, anti-MMP7 polyclonal antibody. MMP7 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, and predicted: rat background without labeling.

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