MMP Inhibitor II
Based on 1 Customer Validation
MMP Inhibitor II (compound 4e) is a potent, reversible pan-MMP inhibitor with IC50 values of 24 nM, 18.4 nM, 30 nM, and 2.7 nM for MMP-1,MMP-3, MMP-7, and MMP-9, respectively.
For research use only. We do not sell to patients.
- Purity: 99.7%
- CAS No.: 203915-59-7
- Formula: C21H27N3O8S2
- Molecular Weight:513.58
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
|
MMP-1 24 nM (IC50) |
MMP-3 18.4 nM (IC50) |
MMP-7 30 nM (IC50) |
MMP-9 2.7 nM (IC50) |
Chemical Information
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CAS No. 203915-59-7
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Appearance Solid
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Molecular Weight 513.58
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Formula C21H27N3O8S2
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Color White to off-white
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SMILES
O=C(C1N(S(=O)(C2=CC=C(C=C2)OC)=O)CC(C)(CN1S(=O)(C3=CC=C(C=C3)OC)=O)C)NO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 20 mg/mL (38.94 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9471 mL | 9.7356 mL | 19.4712 mL | 48.6779 mL |
| 5 mM | 0.3894 mL | 1.9471 mL | 3.8942 mL | 9.7356 mL | |
| 10 mM | 0.1947 mL | 0.9736 mL | 1.9471 mL | 4.8678 mL | |
| 15 mM | 0.1298 mL | 0.6490 mL | 1.2981 mL | 3.2452 mL | |
| 20 mM | 0.0974 mL | 0.4868 mL | 0.9736 mL | 2.4339 mL | |
| 25 mM | 0.0779 mL | 0.3894 mL | 0.7788 mL | 1.9471 mL | |
| 30 mM | 0.0649 mL | 0.3245 mL | 0.6490 mL | 1.6226 mL |