1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Lipoxygenase
  4. 5-LOX Inhibitors

5-LOX Inhibitors

5-LOX

12-LOX

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Sorry. There is currently no product that acts on isoform 5-LOX together.

Please try each isoform separately.

5-LOX Specific Inhibitors, Antagonists & Modulators
Product Name 5-LOX 5-LOX Selectivity Purity
U-73122
5-LOX
Selective Inhibitor 98.17%
Zileuton
5-LOX
Selective Inhibitor 99.58%
Nordihydroguaiaretic acid
5-LOX, IC50: 8 μM
Selective Inhibitor 99.78%
Wedelolactone
5-LOX, IC50: 2.5 μM
Selective Inhibitor 99.91%
Indirubin-3'-monoxime
5-LOX, IC50: 7.8-10 μM
Selective Inhibitor 99.95%
Caffeic acid
5-LO
Selective Inhibitor 98.71%
Lonapalene
5-LO
Selective Inhibitor 99.07%
Psoralidin
5-LOX
Selective Inhibitor 99.90%
Malotilate
5-Lipoxygenase
Selective Inhibitor 99.54%
Docebenone
5-LO
Selective Inhibitor 99.10%
PF-4191834
5-LOX
Selective Inhibitor >99.0%
11-​Keto-​beta-​boswellic acid
5-LOX
Selective Inhibitor 99.96%
S-(+)-Marmesin
5-LOX
Selective Inhibitor 99.04%
Zileuton sodium
5-Lipoxygenase
Selective Inhibitor
Enazadrem
5-Lipoxygenase
Selective Inhibitor 97.26%
PGS-IN-1
5-Lipoxygenase, IC50: 1.05 μM
Selective Inhibitor 99.51%
Cirsiliol
5-Lipoxygenase
Selective Inhibitor
Pectolinarigenin
5-LOX
Selective Inhibitor
Lycopodine
5-Lipoxygenase
Selective Inhibitor
ICI 211965
5-LPO
Selective Inhibitor
β-Boswellic acid
5-LO
Selective Inhibitor
Atreleuton
5-LO
Selective Inhibitor
A-69412
5-LO
Selective Inhibitor
LY 178002
5-LPO, IC50: 0.6 μM
Selective Antagonist
RWJ 63556
5-Lipoxygenase
Selective Inhibitor
S-2474
5-LO
Selective Inhibitor
CMI977
5-LO
Selective Inhibitor
COX/5-LO-IN-1
5-LO, IC50: 2 μM
Selective Inhibitor
CMI-392
5-LO, IC50: 100 nM
Selective Inhibitor
AZD 4407
5-Lipoxygenase
Selective Inhibitor
5-Lipoxygenase-In-1
5-Lipoxygenase
Selective Inhibitor
Bunaprolast
5-LO
Selective Inhibitor
2,5-Di-tert-butylhydroquinone
5-LO, IC50: 1.8 μM
Pan Modulator >98.0%
Phenethyl ferulate
5-LOX, IC50: 5.75 μM
Pan Inhibitor
Licofelone
5-LOX, IC50: 0.18 μM
Pan Inhibitor >99.0%
5-O-Demethylnobiletin
5-LOX, IC50: 0.1 μM
Pan Inhibitor >99.0%