1. Immunology/Inflammation
    Metabolic Enzyme/Protease
  2. COX
    Lipoxygenase
  3. S-(+)-Marmesin

S-(+)-Marmesin (Synonyms: (+)-Marmesin; (S)-Marmesin)

Cat. No.: HY-N2176 Purity: 99.04%
Handling Instructions

S-(+)-Marmesin is a natural coumarin, exhibiting COX-2/5-LOX dual inhibitory activity.

For research use only. We do not sell to patients.

S-(+)-Marmesin Chemical Structure

S-(+)-Marmesin Chemical Structure

CAS No. : 13849-08-6

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2 mg USD 120 In-stock
Estimated Time of Arrival: December 31
5 mg USD 252 In-stock
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10 mg USD 432 In-stock
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25 mg USD 876 In-stock
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50 mg USD 1440 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

S-(+)-Marmesin is a natural coumarin, exhibiting COX-2/5-LOX dual inhibitory activity.

IC50 & Target[2]

COX-2

 

5-LOX

 

In Vitro

S-(+)-Marmesin ((+)-marmesin) shows affinity at the recombinant psoralen synthase, with a Km of 1.5 ± 0.5 μM, exceeding the substrate affinities of other enzymes of the CYP71 subfamily involved in plant secondary metabolism[1]. S-(+)-Marmesin ((+)-marmesin) shows COX-2/5-LOX dual inhibitory activity[2].

Molecular Weight

246.26

Formula

C₁₄H₁₄O₄

CAS No.

13849-08-6

SMILES

O=C1C=CC2=CC3=C(O[[email protected]](C(C)(O)C)C3)C=C2O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 2 mg/mL (8.12 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0607 mL 20.3037 mL 40.6075 mL
5 mM 0.8121 mL 4.0607 mL 8.1215 mL
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

S-(+)-Marmesin(+)-Marmesin(S)-MarmesinCOXLipoxygenaseCyclooxygenaseLOXInhibitorinhibitorinhibit

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S-(+)-Marmesin
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