230961-08-7
230961-08-7
Chemical Structure
UK 356618
- CAS No.: 230961-08-7
- Formula:C34H43N3O4
- Molecular Weight:557.72
IUPAC Name: (R)-N1-((S)-3,3-dimethyl-1-oxo-1-(((R)-1-phenylethyl)amino)butan-2-yl)-N4-hydroxy-2-(3-(2-methyl-[1,1'-biphenyl]-4-yl)propyl)succinamide
InChIKey: JJHRUUKMPWUYIB-HVOSOHGQSA-N
SMILES: CC1=C(C2=CC=CC=C2)C=CC(CCC[C@H](CC(NO)=O)C(N[C@@H](C(C)(C)C)C(N[C@@H](C3=CC=CC=C3)C)=O)=O)=C1
Biological Activity: UK 356618 (Compound 4j) is a potent and selective inhibitor of matrix metalloprotease-3 (MMP-3) with an IC50 of 5.9 nM. UK 356618 is less potent against MMP-1, MMP-2, MMP-9, MMP-13 and MMP-14 compared with MMP-3[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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UK 356618 | 98.51% | UK 356618 (Compound 4j) is a potent and selective inhibitor of matrix metalloprotease-3 (MMP-3) with an IC50 of 5.9 nM. UK 356618 is less potent against MMP-1, MMP-2, MMP-9, MMP-13 and MMP-14 compared with MMP-3. | ||||||||||||||||||||
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