935759-55-0
Chemical Structure
MMP13-IN-2
- CAS No.: 935759-55-0
- Formula:C24H19FN6O4S
- Molecular Weight:506.51
IUPAC Name: N-(3-(2-((1H-1,2,4-triazol-5-yl)oxy)ethoxy)benzyl)-5-(3-fluorophenyl)-4-oxo-1,4-dihydrothieno[2,3-d]pyrimidine-2-carboxamide
InChIKey: MLUCCAMJMIYYED-UHFFFAOYSA-N
SMILES: O=C(C(NC1=C2C(C3=CC=CC(F)=C3)=CS1)=NC2=O)NCC4=CC=CC(OCCOC5=NC=NN5)=C4
Biological Activity: MMP13-IN-2 is a potent, selective and orally active MMP-13 inhibitor. MMP13-IN-2 exhibits excellent potency for MMP-13 (IC50=0.036 nM) and selectivities (greater than 1,500-fold) over MMP-1, 3, 7, 8, 9, 14, and TACE. MMP13-IN-2 has the ability to block the release of collagen from cartilage in vitro. MMP13-IN-2 has the potential for collagenase related disease research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MMP13-IN-2 | 99.13% | MMP13-IN-2 is a potent, selective and orally active MMP-13 inhibitor. MMP13-IN-2 exhibits excellent potency for MMP-13 (IC50=0.036 nM) and selectivities (greater than 1,500-fold) over MMP-1, 3, 7, 8, 9, 14, and TACE. MMP13-IN-2 has the ability to block the release of collagen from cartilage in vitro. MMP13-IN-2 has the potential for collagenase related disease research. | ||||||||||||||||||||
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