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Cat. No.: HY-115721

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Antimalarial agent 2

Antimalarial agent 2 is a novel orally efficacious antimalarials that suggests a fast in vitro killing profile.

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CAS No.: 2829950-49-2
화학식: C₂₇H₂₅N₃O₅
분자량:471.50

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Antimalarial agent 2 Chemical Structure

CAS No.: 2829950-49-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Antimalarial agent 2 is a novel orally efficacious antimalarials that suggests a fast in vitro killing profile.

IC₅₀ & Target

Plasmodium

All Parasite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	CC₅₀	>40 μM Compound: 19f	Cytotoxicity against human HEK293 cells assessed as cell viability incubated for 72 hrs by Alamar blue assay Cytotoxicity against human HEK293 cells assessed as cell viability incubated for 72 hrs by Alamar blue assay	[PMID: 34437804]

Chemical Information

CAS No. 2829950-49-2
분자량 471.50
화학식 C₂₇H₂₅N₃O₅
SMILES

O=C(O)C1=CC=C(COCC2=CC=CC(N=C(C(NCC3=CC=CC(CC)=C3)=O)N4)=C2C4=O)C=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Laleu B, et al. Discovery and Structure-Activity Relationships of Quinazolinone-2-carboxamide Derivatives as Novel Orally Efficacious Antimalarials. J Med Chem. 2021 Sep 9;64(17):12582-12602. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

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Antimalarial agent 2

All Parasite Isoforms