1. Metabolic Enzyme/Protease
  2. MMP
  3. Luteolin 7-O-glucuronide

Luteolin 7-O-glucuronide (Synonyms: Luteolin 7-glucuronide)

Cat. No.: HY-N1463 Purity: 99.80%
Handling Instructions

Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively.

For research use only. We do not sell to patients.

Luteolin 7-O-glucuronide Chemical Structure

Luteolin 7-O-glucuronide Chemical Structure

CAS No. : 29741-10-4

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 99 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 99 In-stock
Estimated Time of Arrival: December 31
Solid
5 mg USD 90 In-stock
Estimated Time of Arrival: December 31
10 mg USD 150 In-stock
Estimated Time of Arrival: December 31
25 mg USD 330 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively.

IC50 & Target

MMP-1

17.63 μM (IC50)

MMP-3

7.99 μM (IC50)

MMP-8

11.42 μM (IC50)

MMP-9

12.85 μM (IC50)

MMP13

0.03 μM (IC50)

Molecular Weight

462.36

Formula

C₂₁H₁₈O₁₂

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (270.35 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1628 mL 10.8141 mL 21.6282 mL
5 mM 0.4326 mL 2.1628 mL 4.3256 mL
10 mM 0.2163 mL 1.0814 mL 2.1628 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  0.5% MC  0.5% Tween-80

    Solubility: 15.71 mg/mL (33.98 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  50% PEG300    50% saline

    Solubility: 5 mg/mL (10.81 mM); Clear solution; Need ultrasonic

  • 3.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (4.50 mM); Clear solution

  • 4.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (4.50 mM); Clear solution

  • 5.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.50 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.80%

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Product Name:
Luteolin 7-O-glucuronide
Cat. No.:
HY-N1463
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