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FITC-Dextran (MW 40000)

16 Cited Publications
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Based on 16 publication(s) in Google Scholar

FITC-Dextran (MW 40000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 40000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 40000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption.

For research use only. We do not sell to patients.

  • CAS No.: 60842-46-8
  • Molecular Weight:40000(Average)
  • Storage:

    4°C, protect from light

    * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

  • FITC-Dextran (MW 40000) Chemical Structure
    FITC-Dextran (MW 40000) Chemical Structure
  • Experimental Validation Results for FITC-Dextran (MW 40000)
  • Experimental Validation Results for FITC-Dextran (MW 40000)
  • Experimental Validation Results for FITC-Dextran (MW 40000)
  • Experimental Validation Results for FITC-Dextran (MW 40000)
  • Experimental Validation Results for FITC-Dextran (MW 40000)
CAS No.: 60842-46-8
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Publications Citing Use of MedChemExpress (MCE) FITC-Dextran (MW 40000)

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Bio/Physico-chemical AssayCell Imaging/StainingIn Vivo ImagingFlow Cytometry2D/3D Cell Culture and Differentiation
  • Bio/Physico-chemical Assay
  • Cell Imaging/Staining
  • Flow Cytometry
  • 2D/3D Cell Culture and Differentiation
  • In Vivo Imaging
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  • FITC-Dextran (MW 40000) Chemical Structure
    FITC-Dextran (MW 40000) Chemical Structure
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    FITC-Dextran (MW 40000) purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Aug;12(30):e00461. [Abstract]

    Customer Validation
     The plasma FD4 level in Acss2CKO and Acss2fl/fl mice (n = 7). For intestinal permeability assessment, mice were fasted for 8 h, followed by oral administration of FITC‑Dextran (MW 40000, 0.6 mg/g body weight). Four hours after gavage, mice were sacrificed, and plasma samples were collected for fluorescence intensity measurement at 490 nm. A standard curve of FD40000 was used to calculate the plasma concentration. Intestinal permeability was obviously impaired in Acss2CKO mice, as determined by FD4 (FITC‑Dextran, MW 40000) gavage.

  • 1/16

    FITC-Dextran (MW 40000) purchased from MedChemExpress. Usage Cited in: Biomaterials. 2025 Sep 17:326:123723. [Abstract]

    Customer Validation
     The time-dependent variations of normalized fluorescence of FITC-Dextran (40, 70, 150 kDa; 0.5 mg/mL) and FITC-BSA in TNHs with Cp of 70 mg/mL. The inset shows confocal microscopic images of TNHs containing FITC-BSA at different time points after the photo-bleaching in FRAP experiments. The Cp is 70 mg/mL. Scale bar, 50 μm.

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    FITC-Dextran (MW 40000) purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2025 Dec 31.

    Customer Validation
     The phagocytic activity was analyzed using FITC-Dextran (MW 40000) (1 mg/mL; 30 min) by flow cytometry. The values are presented as mean ± SD (n = 3). Significant differences with the control group (Ctrl) were designated as ⁎⁎⁎P < 0.001. The figure shown is representative of three independent experiments.

  • 1/16

    FITC-Dextran (MW 40000) purchased from MedChemExpress. Usage Cited in: Food Biosci. 2025 Aug 30;72:107512.

    Customer Validation
     FITC-Dextran (MW 40000) (1 mg/mL; 6 h) test results of the fluorescence intensity of the solution under the Caco-2 cell barrier. The experiment was repeated six times, n = 6; with “∗” representing P < 0.05; P < 0.05 is considered to indicate a statistically significant difference.

  • 1/16

    FITC-Dextran (MW 40000) purchased from MedChemExpress. Usage Cited in: J Control Release. 2024 Nov:375:698-711. [Abstract]

    Customer Validation
     Representative images of fluorescein isothiocyanate-conjugated dextran (FITC-Dextran (MW 40000), 100 μg; i.v.; single dose) distribution in normal and infected lung tissues with different treatments. Scale bar: 50 μm.

  • FITC-Dextran (MW 40000)