D-Phenothrin  (Synonyms: (-)-trans-Phenothrin)

D-Phenothrin ((-)-trans-Phenothrin), an orally active Type II synthetic pyrethroid, is widely used to kill insects, mosquitoes, and human lice. D-Phenothrin is also used in veterinary medicine to control insect pests on animals and protect agricultural crops^[1].

D-Phenothrin ((-)-trans-Phenothrin; 25-200 mg/kg; IP; 14 consecutive days) significantly, dose-dependently increases oxidative DNA damage in both organs of animals^[1].
D-Phenothrin (100, 300 or 1000 mg/kg/day; p.o.; 3 days) exhibits no potential to cause adverse estrogenic or (anti-)androgenic effects^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

350.45

C₂₃H₂₆O₃

26046-85-5

O=C([C@H]1C(C)(C)[C@@H]1/C=C(C)\C)OCC2=CC=CC(OC3=CC=CC=C3)=C2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Atmaca E, et al. d-Phenothrin-induced oxidative DNA damage in rat liver and kidney determined by HPLC-ECD/DAD. Environ Toxicol. 2015 May;30(5):607-13.  [Content Brief]

  [2]. Yamada T, et al. Lack of estrogenic or (anti-)androgenic effects of d-phenothrin in the uterotrophic and Hershberger assays. Toxicology. 2003 Apr 22;186(3):227-39.  [Content Brief]