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Cat. No.: HY-146982

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hCAII-IN-1

hCAII-IN-1 (compound 7f) is a potent and selective inhibitor of carbonic anhydrase (CA II/IX) with K_is of 1.2 and 113.6 nM, respectively. hCAII-IN-1 has the potential for the research of cancer diseases.

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CAS No.: 1807520-24-6
Formule: C₂₁H₂₁BrN₆O₄S
Masse moléculaire:533.40

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

hCAII-IN-1 Chemical Structure

CAS No.: 1807520-24-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Voir tous les produits spécifiques à Isoform Carbonic Anhydrase :

Chemical Information

CAS No. 1807520-24-6
Masse moléculaire 533.40
Formule C₂₁H₂₁BrN₆O₄S
SMILES

NS(=O)(OC1=CC=C(C=C1)NC(N2CCN(CC2)C3=NC(C4=CC=C(C=C4)Br)=CC=N3)=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Nocentini A, et al. Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors. Eur J Med Chem. 2020;186:111896. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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hCAII-IN-1

Voir tous les produits spécifiques à Isoform Carbonic Anhydrase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

hCAII-IN-1 Related Classifications

HY-146982 Related Classifications