MNI137
Based on 1 Customer Validation
MNI137 is a potent and selective negative allosteric modulator for group II mGluRs. MNI137 has IC50s values of 8.3 and 12.6 nM for human and rat mGlu2 inhibition of glutamate-induced calcium mobilization.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 946619-21-2
- Formula: C15H9BrN4O
- Molecular Weight:341.16
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 946619-21-2
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Appearance Solid
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Molecular Weight 341.16
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Formula C15H9BrN4O
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Color Light brown to brown
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SMILES
N#CC1=NC=CC(C2=NC3=CC=C(Br)C=C3NC(C2)=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 83.33 mg/mL (244.25 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.9312 mL | 14.6559 mL | 29.3118 mL | 73.2794 mL |
| 5 mM | 0.5862 mL | 2.9312 mL | 5.8624 mL | 14.6559 mL | |
| 10 mM | 0.2931 mL | 1.4656 mL | 2.9312 mL | 7.3279 mL | |
| 15 mM | 0.1954 mL | 0.9771 mL | 1.9541 mL | 4.8853 mL | |
| 20 mM | 0.1466 mL | 0.7328 mL | 1.4656 mL | 3.6640 mL | |
| 25 mM | 0.1172 mL | 0.5862 mL | 1.1725 mL | 2.9312 mL | |
| 30 mM | 0.0977 mL | 0.4885 mL | 0.9771 mL | 2.4426 mL | |
| 40 mM | 0.0733 mL | 0.3664 mL | 0.7328 mL | 1.8320 mL | |
| 50 mM | 0.0586 mL | 0.2931 mL | 0.5862 mL | 1.4656 mL | |
| 60 mM | 0.0489 mL | 0.2443 mL | 0.4885 mL | 1.2213 mL | |
| 80 mM | 0.0366 mL | 0.1832 mL | 0.3664 mL | 0.9160 mL | |
| 100 mM | 0.0293 mL | 0.1466 mL | 0.2931 mL | 0.7328 mL |
MNI137 Related Classifications
HY-103572 Related Classifications
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