1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. mGluR
  4. mGluR3 Inhibitors

mGluR3 Inhibitors

mGluR1

mGluR2

mGluR3

mGluR4

mGluR5

mGluR6

mGluR7

mGluR8

mGluR

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform mGluR3 together.

Please try each isoform separately.

mGluR3 Specific Agonists, Antagonists & Modulators
Product Name mGluR3 mGluR1 mGluR2 mGluR4 mGluR5 mGluR6 mGluR7 mGluR8 mGluR3 Selectivity Purity
VU0650786
mGluR3, IC50: 392 nM
              Selective Antagonist 99.97%
LY2794193
mGluR3, EC50: 0.47 nM
mGluR3, Ki: 0.927 nM
 
mGluR2, EC50: 47.5
mGluR2, Ki: 412
          Selective Agonist 99.88%
MSOP
mGluR3, Kd: 51 μM
              Selective Antagonist
LY 541850
mGluR3, IC50: 1.05 μM
 
mGluR2, IC50: 0.161 μM
          Selective Antagonist
LY341495
mGluR3, IC50: 14 nM
mGluR1a, IC50: 7.8 μM
mGluR2, IC50: 21 nM
mGluR4, IC50: 22 μM
mGluR5a, IC50: 8.2 μM
 
mGluR7, IC50: 990 nM
mGluR8, IC50: 170 nM
Pan Antagonist 99.11%
Eglumegad
mGluR3R, IC50: 24 nM
 
mGluR2R, IC50: 5 nM
          Pan Agonist >98.0%
Pomaglumetad methionil hydrochloride
mGluR3
 
mGluR2
          Pan Agonist 98.20%
Xanthurenic acid
mGluR3
 
mGluR2
          Pan Agonist 98.17%
LY404039
hmGluR3, Ki: 92 nM
 
mGlu2 Receptor, Ki: 149 nM (Recombinant human mGluR2)
          Pan Agonist >98.0%
Decoglurant
mGluR3
 
mGluR2
          Pan Modulator 99.71%
LY2812223
mGluR3, Ki: 156 nM
 
mGluR2, Ki: 144 nM
          Pan Agonist >98.0%
DCG-IV
mGluR3R, EC50: 0.09 μM
mGluR1R, IC50: 389 μM
mGluR2R, EC50: 0.35 μM
mGluR4R, IC50: 22.5 μM
mGluR5, IC50: 630 μM
mGluR6, IC50: 39.6 μM
mGluR7, IC50: 40.1 μM
mGluR8, IC50: 32 μM
Pan Agonist
LY3020371
hmGluR3, Ki: 2.50 nM
 
hmGluR2, Ki: 5.26 nM
          Pan Antagonist
Pomaglumetad methionil anhydrous
mGluR3
 
mGluR2
          Pan Agonist