1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. mGluR
  4. mGluR3 Inhibitors

mGluR3 Inhibitors

mGluR8

mGluR6

mGluR7

mGluR5

mGluR4

mGluR3

mGluR2

mGluR1

mGluR

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform mGluR3 together.

Please try each isoform separately.

mGluR3 Specific Inhibitors, Agonists, Antagonists & Modulators
Product Name mGluR3 mGluR8 mGluR6 mGluR7 mGluR5 mGluR4 mGluR2 mGluR1 mGluR3 Selectivity Purity
VU0650786
mGluR3, IC50: 392 nM
              Selective Antagonist 99.97%
LY2794193
mGluR3, EC50: 0.47 nM
mGluR3, Ki: 0.927 nM
         
mGluR2, EC50: 47.5
mGluR2, Ki: 412
  Selective Agonist 99.88%
LY3020371 hydrochloride
mGluR3, Ki: 2.5 nM
         
mGluR2, Ki: 5.3 nM
  Selective Antagonist
ML337
mGluR3, IC50: 593 nM
              Selective Modulator
MSOP
mGluR3, Kd: 51 μM
              Selective Antagonist
LY 541850
mGluR3, IC50: 1.05 μM
         
mGluR2, IC50: 0.161 μM
  Selective Antagonist
ML289
mGluR3, IC50: 0.66 μM
              Selective Inhibitor
Eglumegad
mGluR3R, IC50: 24 nM
         
mGluR2R, IC50: 5 nM
  Pan Agonist >98.0%
LY341495
mGluR3, IC50: 14 nM
mGluR8, IC50: 170 nM
 
mGluR7, IC50: 990 nM
mGluR5a, IC50: 8.2 μM
mGluR4, IC50: 22 μM
mGluR2, IC50: 21 nM
mGluR1a, IC50: 7.8 μM
Pan Antagonist 99.11%
Decoglurant
mGluR3
         
mGluR2
  Pan Modulator 99.71%
Xanthurenic acid
mGluR3
         
mGluR2
  Pan Agonist 98.17%
LY2812223
mGluR3, Ki: 156 nM
         
mGluR2, Ki: 144 nM
  Pan Agonist >98.0%
Pomaglumetad methionil
mGluR3
         
mGluR2
  Pan Agonist
DCG-IV
mGluR3R, EC50: 0.09 μM
mGluR8, IC50: 32 μM
mGluR6, IC50: 39.6 μM
mGluR7, IC50: 40.1 μM
mGluR5, IC50: 630 μM
mGluR4R, IC50: 22.5 μM
mGluR2R, EC50: 0.35 μM
mGluR1R, IC50: 389 μM
Pan Agonist
LY2140023
mGluR3
         
mGluR2
  Pan Agonist
MGS0274
mGluR3
         
mGluR2
  default Agonist