1443118-44-2
Chemical Structure
ML337
- CAS No.: 1443118-44-2
- Formula:C21H20FNO3
- Molecular Weight:353.39
IUPAC Name: (R)-(2-fluoro-4-((4-methoxyphenyl)ethynyl)phenyl)(3-hydroxypiperidin-1-yl)methanone
InChIKey: QBCRLDPMQHPGIM-QGZVFWFLSA-N
SMILES: O=C(C1=CC=C(C#CC2=CC=C(OC)C=C2)C=C1F)N3C[C@H](O)CCC3
Biological Activity: ML337 is a selective and brain-penetrant negative allosteric modulator of mGlu3, with an IC50 of 593 nM. ML337 possesses a favorable dystrophia myotonica protein kinase (DMPK) and ancillary pharmacology profile[1]. ML337 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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ML337 | 99.04% | ML337 is a selective and brain-penetrant negative allosteric modulator of mGlu3, with an IC50 of 593 nM. ML337 possesses a favorable dystrophia myotonica protein kinase (DMPK) and ancillary pharmacology profile. ML337 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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