1809085-30-0
1809085-30-0
Chemical Structure
VU0650786
- CAS No.: 1809085-30-0
- Formula:C18H15ClFN5O2
- Molecular Weight:387.80
IUPAC Name: (R)-2-(((5-chloropyridin-2-yl)oxy)methyl)-5-(2-fluoropyridin-3-yl)-7-methyl-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one
InChIKey: RXRVCJFGSOVYLG-LLVKDONJSA-N
SMILES: ClC1=CN=C(OCC2=NN([C@H](C)CN(C3=C(F)N=CC=C3)C4=O)C4=C2)C=C1
Biological Activity: VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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VU0650786 | 99.55% | VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents. | ||||||||||||||||||||
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VU0650786 (Standard) | ≥98% | VU0650786 (Standard) is the analytical standard of VU0650786 (HY-108710). This product is intended for research and analytical applications. VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents. | ||||||||||||||||||||
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