201943-63-7
201943-63-7
Chemical Structure
LY341495
- CAS No.: 201943-63-7
- Formula:C20H19NO5
- Molecular Weight:353.37
IUPAC Name: (1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl)cyclopropane-1-carboxylic acid
InChIKey: VLZBRVJVCCNPRJ-KPHUOKFYSA-N
SMILES: O=C(O)[C@@H]1[C@H](C1)[C@@](N)(CC2C3=C(C=CC=C3)OC4=C2C=CC=C4)C(O)=O
Biological Activity: LY341495 is a metabotropic glutamate receptor (mGluR) antagonist with IC50s of 21 nM, 14 nM, 7.8 μM, 8.2 μM, 170 nM, 990 nM, 22 μM for mGlu2, mGlu3, mGlu1a, mGlu5a, mGlu8, mGlu7, and mGlu4 receptors, respectively[5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
LY341495 | 99.70% | LY341495 is a metabotropic glutamate receptor (mGluR) antagonist with IC50s of 21 nM, 14 nM, 7.8 μM, 8.2 μM, 170 nM, 990 nM, 22 μM for mGlu2, mGlu3, mGlu1a, mGlu5a, mGlu8, mGlu7, and mGlu4 receptors, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 1.00
HY-70059A(Rac)-LY341495 -
Similarity Score 0.63
HY-123253cis-LY393053 -
Similarity Score 0.58
HY-Y0447RXanthenecarboxylic acid (Standard) -
Similarity Score 0.55
HY-78996Methyl 9H-xanthene-9-carboxylate -
Similarity Score 0.54
HY-B1689AMethantheline bromide -
Similarity Score 0.52
HY-B1188Propantheline bromide -
Similarity Score 0.51
HY-171471SKF 10810 -
Similarity Score 0.50
HY-10121BAsenapine citrate -
Similarity Score 0.49
HY-116701A 274 -
Explore the MedChemAI to find more analogs
