Methantheline bromide
Methantheline bromide is a quaternary Ammonium derivate with anticholinergic activity. Methantheline bromide results in a significant greater reduction of axillary sweat production. Methyl bromide can be used in the research of intractable peptic ulcers.
For research use only. We do not sell to patients.
- CAS No.: 53-46-3
- Formula: C21H26BrNO3
- Molecular Weight:420.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Caco-2 | Inhibition |
3.37 %
Compound: METHANTHELINE
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Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging
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10.21203/rs.3.rs-23951/v1 |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 53-46-3
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Molecular Weight 420.34
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Formula C21H26BrNO3
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SMILES
O=C(OCC[N+](CC)(CC)C)C1C2=C(OC3=C1C=CC=C3)C=CC=C2.[Br-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. LIEBOWITZ D, et al. Treatment of intractable peptic ulcer with methantheline (banthine) bromide. J Am Med Assoc. 1952 Oct 18;150(7):672-8. English, Undetermined Language. [Content Brief]
[2]. Müller C, et al. Efficacy and safety of methantheline bromide (Vagantin(®) ) in axillary and palmar hyperhidrosis: results from a multicenter, randomized, placebo-controlled trial. J Eur Acad Dermatol Venereol. 2013 Oct;27(10):1278-84. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Methantheline bromide Related Classifications
HY-B1689A Related Classifications
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