1. GPCR/G Protein
    Neuronal Signaling
  2. mGluR
  3. VU6001966

VU6001966 

Cat. No.: HY-120717
Handling Instructions

VU6001966 (compound 15m) is a potent and cross the blood-brain barrier mGlu2 (metabotropic glutamate receptor 2) negative allosteric modulator with IC50s of 78 nM and >30 µM for mGlu2 and mGlu3, respectively. VU6001966 can serve as an mGlu2 PET tracer.

For research use only. We do not sell to patients.

VU6001966 Chemical Structure

VU6001966 Chemical Structure

CAS No. : 2009052-76-8

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Description

VU6001966 (compound 15m) is a potent and cross the blood-brain barrier mGlu2 (metabotropic glutamate receptor 2) negative allosteric modulator with IC50s of 78 nM and >30 µM for mGlu2 and mGlu3, respectively. VU6001966 can serve as an mGlu2 PET tracer[1].

IC50 & Target[1]

mGluR2

78 nM (IC50)

mGluR3

>30 μM (IC50)

Molecular Weight

326.33

Formula

C17H15FN4O2

CAS No.
SMILES

O=C(C1=NC=C(OCC2=NN(C)C=C2)C(C3=CC=C(F)C=C3)=C1)N

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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VU6001966
Cat. No.:
HY-120717
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