2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Cytochrome P450
  5. CYP2 Isoform

CYP2

 

CYP2 Related Products (53):

Cat. No. Product Name Effect Purity
  • HY-N1201
    Apigenin
    		Inhibitor 99.22%
    Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a Ki of 2 μM.
  • HY-17356
    Fenofibrate
    		Inhibitor 99.99%
    Fenofibrate is a selective PPARα agonist with an EC50 of 30 μM.
  • HY-B0876
    Fomepizole
    		Inhibitor 99.67%
    Fomepizole (4-Methylpyrazole) is a potent cytochrome P450 (CYP2E1) inhibitor.
  • HY-N0319
    Salvianolic acid C
    		Inhibitor 99.94%
    Salvianolic acid C is a noncompetitive Cytochrome P4502C8 (CYP2C8) inhibitor and a moderate mixed inhibitor of Cytochrome P45022J2 (CYP2J2), with Kis of 4.82 μM and 5.75 μM for CYP2C8 and CYP2J2, respectively.
  • HY-129993
    Gemfibrozil 1-O-β-glucuronide
    		Inhibitor 98.71%
    Gemfibrozil 1-O-β-Glucuronide, a metabolite of Gemfibrozil (CI-719; HY-B0258), is a potent and competitive P450 (CYP) isoform CYP2C8 inhibitor with an IC50 of 4.07 μM.
  • HY-152159
    CYP4Z1-IN-1
    		Inhibitor
    CYP4Z1-IN-1 (compound 7c) is a potent CYP4Z1 inhibitor, with an IC50 of 41.8 nM.
  • HY-18063
    ML252
    		Inhibitor
    ML252 is a selective inhibitor of potassium channel, targeting to KCNQ2 channel (Kv7.2) (IC50=69 nM).
  • HY-148597
    FGFR-IN-10
    		Inhibitor
    FGFR-IN-10 is an orally active inhibitor of FGFR and Cytochrome P450 (CYPs).
  • HY-B0258
    Gemfibrozil
    		Inhibitor 99.91%
    Gemfibrozil is an activator of PPAR-α, used as a lipid-lowering drug; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with Ki values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively.
  • HY-N0043
    Ginsenoside Rd
    		Inhibitor 98.02%
    Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC50 of 12.05±0.82 μM in HepG2 cells.
  • HY-N2194
    Bergamottin
    		Inhibitor 99.80%
    Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM.
  • HY-131968
    BMS-986202
    		Inhibitor 99.92%
    BMS-986202 is a potent, selective and orally active Tyk2 inhibitor that binds to Tyk2 JH2 with an IC50 of 0.19 nM and a Ki of 0.02 nM.
  • HY-B1184A
    (S)-Mephenytoin
    		99.81%
    (S)-Mephenytoin ((+)-Mephenytoin) is an anticonvulsive agent.
  • HY-17459
    Clopidogrel hydrogen sulfate
    		Inhibitor 99.75%
    Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots.
  • HY-W008364
    Olivetol
    		Inhibitor 99.81%
    Olivetol is a naturally phenol found in lichens and produced by certain insects, acting as a competitive inhibitor of the cannabinoid receptors CB1 and CB2.
  • HY-N0692
    Schisandrol B
    		Inhibitor 99.57%
    Schisandrol B (Gomisin-A) is a major active constituent of Schisandra chinensis with hepato-protective effects.
  • HY-B1184
    Mephenytoin
    		99.96%
    Mephenytoin, an anticonvulsant, is the CYP2C19 and CYP2B6 substrate.
  • HY-N0482
    Phillyrin
    		Activator 98.82%
    Phillyrin is isolated from Forsythia suspensa Vahl (Oleaceae), has antibacterial and anti-inflammatory activities.
  • HY-N0904
    Ginsenoside C-K
    		98.04%
    Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2.
  • HY-N0893
    Tetrahydrocurcumin
    		Inhibitor 99.43%
    Tetrahydrocurcumin is a Curcuminoid found in turmeric (Curcuma longa) that is produced by the reduction of Curcumin.