70989-04-7
70989-04-7
Chemical Structure
(S)-Mephenytoin
Synonym(s): (+)-Mephenytoin
- CAS No.: 70989-04-7
- Formula:C12H14N2O2
- Molecular Weight:218.25
IUPAC Name: (S)-5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione
InChIKey: GMHKMTDVRCWUDX-LBPRGKRZSA-N
SMILES: O=C1N(C)C([C@@](C2=CC=CC=C2)(CC)N1)=O
Biological Activity: (S)-Mephenytoin ((+)-Mephenytoin) is an anticonvulsive agent. (S)-Mephenytoin is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. (S)-Mephenytoin can be used for the analysis of cytochrome P450 metabolism[1][2].
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(S)-Mephenytoin | 99.94% | (S)-Mephenytoin ((+)-Mephenytoin) is an anticonvulsive agent. (S)-Mephenytoin is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. (S)-Mephenytoin can be used for the analysis of cytochrome P450 metabolism. | ||||||||||||||||||||
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(S)-Mephenytoin (Standard) | 99.93% | (S)-Mephenytoin (Standard) is the analytical standard of (S)-Mephenytoin. This product is intended for research and analytical applications. (S)-Mephenytoin ((+)-Mephenytoin) is an anticonvulsive agent. (S)-Mephenytoin is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. (S)-Mephenytoin can be used for the analysis of cytochrome P450 metabolism. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-126043(R)-Mephenytoin -
Similarity Score 1.00
HY-B1184Mephenytoin -
Similarity Score 0.82
HY-W008772R4-Hydroxymephenytoin (Standard) -
Similarity Score 0.82
HY-W587570(S)-4-Hydroxymephenytoin -
Similarity Score 0.81
HY-B1184SMephenytoin-d3 -
Similarity Score 0.81
HY-B1184S3Mephenytoin-13C,d3 -
Similarity Score 0.79
HY-165469Methetoin -
Similarity Score 0.73
HY-137258(±)-N-3-Benzylnirvanol -
Similarity Score 0.73
HY-137258A(R)-N-3-Benzylnirvanol -
Explore the MedChemAI to find more analogs
References
- [1]. Shimada T, et, al. Human liver microsomal cytochrome P-450 mephenytoin 4-hydroxylase, a prototype of genetic polymorphism in oxidative drug metabolism. Purification and characterization of two similar forms involved in the reaction. J Biol Chem. 1986 Jan 15;261(2):909-21. [Content Brief]
- [2]. Goldstein JA, et, al. Evidence that CYP2C19 is the major (S)-mephenytoin 4'-hydroxylase in humans. Biochemistry. 1994 Feb 22;33(7):1743-52. [Content Brief]
