25812-30-0
Chemical Structure
Gemfibrozil
Synonym(s): CI-719
- CAS No.: 25812-30-0
- Formula:C15H22O3
- Molecular Weight:250.33
IUPAC Name: 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid
InChIKey: HEMJJKBWTPKOJG-UHFFFAOYSA-N
SMILES: O=C(O)C(C)(C)CCCOC1=CC(C)=CC=C1C
Biological Activity: Gemfibrozil is an activator of PPAR-α, used as a lipid-lowering agent; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with Ki values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Gemfibrozil | 99.89% | Gemfibrozil is an activator of PPAR-α, used as a lipid-lowering agent; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with Ki values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively. | ||||||||||||||||||||
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Gemfibrozil (Standard) | 99.82% | Gemfibrozil (Standard) is the analytical standard of Gemfibrozil. This product is intended for research and analytical applications. Gemfibrozil is an activator of PPAR-α, used as a lipid-lowering agent; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with Ki values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively. | ||||||||||||||||||||
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Gemfibrozil-d6 | Gemfibrozil-d6 is the deuterium labeled Gemfibrozil. Gemfibrozil is an activator of PPAR-α, used as a lipid-lowering agent; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with Ki values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively. | |||||||||||||||||||||
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Gemfibrozil-d6-1 | Gemfibrozil-d6-1 (CI-719-d6-1) is the deuterium labeled Gemfibrozil (HY-B0258). Gemfibrozil is an activator of PPAR-α, used as a lipid-lowering agent; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with Ki values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively. | |||||||||||||||||||||
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