1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. mGluR
  4. mGluR5 Inhibitors

mGluR5 Inhibitors

mGluR8

mGluR6

mGluR7

mGluR5

mGluR4

mGluR2

mGluR3

mGluR1

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform mGluR5 together.

Please try each isoform separately.

mGluR5 Specific Inhibitors, Agonists, Antagonists & Modulators
Product Name mGluR5 mGluR6 mGluR4 mGluR1 mGluR5 Selectivity Purity
CHPG sodium salt
mGlu5
      Selective Agonist
CHPG
mGlu5
      Selective Agonist
VU0652835
mGlu5, IC50: 81 nM
      Selective Inhibitor
Fenobam
rat mGluR5, Kd: 54 nM
human mGluR5, Kd: 31 nM
      Selective Antagonist 98.53%
DHPG
mGluR 5
   
mGluR 1
Pan Agonist >97.0%
VU0364770
mGlu5, EC50: 17.9 μM
mGlu6, EC50: 6.8 μM
Rat mGlu4, EC50: 290 nM
Human mGlu4, EC50: 1.1 μM
  Pan Agonist 99.57%
(R)-ADX-47273
mGlu5, EC50: 168 nM
      Pan Modulator 99.25%
VU0364770 hydrochloride
mGlu5, EC50: 17.9 μM
mGlu6, EC50: 6.8 μM
Rat mGlu4, EC50: 290 nM
Human mGlu4, EC50: 1.1 μM
  Pan Agonist
FTIDC
mGlu5, IC50: 6200 nM
   
mGluR1a, IC50: 5.8 nM
Pan Inhibitor