1. GPCR/G Protein
    Neuronal Signaling
  2. mGluR
  3. CDPPB

CDPPB 

Cat. No.: HY-14569
Handling Instructions

CDPPB is a potent, selective and brain penetrant positive allosteric modulator of the metabotropic glutamate receptor subtype 5 (mGluR5), with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5. CDPPB may provide an approach for development of antipsychotic agents.

For research use only. We do not sell to patients.

CDPPB Chemical Structure

CDPPB Chemical Structure

CAS No. : 781652-57-1

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Description

CDPPB is a potent, selective and brain penetrant positive allosteric modulator of the metabotropic glutamate receptor subtype 5 (mGluR5), with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5. CDPPB may provide an approach for development of antipsychotic agents[1].

IC50 & Target[1]

mGluR5

27 nM (EC50)

Molecular Weight

364.40

Formula

C₂₃H₁₆N₄O

CAS No.

781652-57-1

SMILES

O=C(NC1=CC(C2=CC=CC=C2)=NN1C3=CC=CC=C3)C4=CC=CC(C#N)=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

CDPPBmGluRMetabotropic glutamate receptorspositiveallostericmetabotropicglutamatereceptorsubtype5mGluR5antipsychoticInhibitorinhibitorinhibit

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